Tanner Health First in US to Use PMcardio AI Platform for Heart Attack Care

The first commercial U.S. deployment of Powerful Medical's FDA-authorized PMcardio platform brings Queen of Hearts™ AI ECG model to EMS, emergency departments and cardiology workflows

CARROLLTON, Ga--(BUSINESS WIRE)--Patients with suspected heart attacks across west Georgia and east Alabama will now have access to artificial intelligence-powered electrocardiogram (ECG) assessment whether their first medical contact occurs in a 911 ambulance, a community hospital or a cardiac center, following Tanner Health's deployment of Powerful Medical's PMcardio platform.

The rollout marks the first commercial United States deployment of Queen of Hearts, Powerful Medical's newly FDA-authorized AI ECG model for urgent acute coronary syndrome, and brings the technology into routine clinical care just days after its FDA De Novo authorization.

“We are proud to be the first healthcare organization in the United States to adopt the PMcardio platform,” said Loy Howard, president and CEO of Tanner Health. “Healthliant Ventures, which is the innovation arm of Tanner, aims to improve access, transform care and empower professionals for higher quality and better efficiency. PMcardio aligns closely with all of this — helping to detect acute heart attacks from ECGs and improving outcomes. This technology builds on our continued investment in cardiovascular care, ensuring that patients move quickly from initial assessment to the specialized teams and advanced capabilities available at Tanner and Adams Heart Center.”

A heart attack occurs approximately every 40 seconds in the United States. However, conventional ECG interpretation can fail to identify acute coronary occlusions that do not meet traditional ST-elevation myocardial infarction (STEMI) criteria, potentially delaying recognition and treatment.

Through integration with Tanner's Epic electronic health record and EMS workflows, PMcardio embeds Queen of Hearts into existing clinical pathways. When a patient receives a 12-lead ECG in a Tanner ambulance or emergency department, the AI assessment is a secondary support to clinical decision-making and, where appropriate, earlier cardiology consultation and cardiac catheterization.

“This deployment reflects Tanner’s commitment to bringing advanced cardiac care closer to the communities we serve,” said LaQuinta Grizzard, MSN, RN, NE-BC, AACC, vice president of Heart and Vascular Services at Tanner Health. “By integrating PMcardio and the Queen of Hearts AI ECG model across EMS, emergency departments and cardiology workflows, our clinicians have another decision-support tool to help recognize high-risk heart attack presentations earlier, including cases that may not meet traditional STEMI criteria. That shared insight can help support faster evaluation, more informed escalation and timely access to the right level of care.”

Moving Beyond Conventional STEMI Criteria

Queen of Hearts is supported by more than 20 peer-reviewed studies encompassing more than 40,000 patients across four continents. In a multicenter U.S. study of 1,032 patients published in JACC: Cardiovascular Interventions, Queen of Hearts identified 553 of 601 confirmed STEMIs from the initial ECG, compared with 427 through standard triage, while reducing the false-positive rate from 41.8% to 7.9%.

“Regulatory authorization tells clinicians a technology is safe and effective, but the real test is whether it changes what happens to the patient in front of them,” said Robert Herman, MD, PhD, chief medical officer and co-founder of Powerful Medical. “With Tanner, Queen of Hearts is entering routine clinical practice in the United States for the first time, giving paramedics, emergency physicians and cardiologists a shared, objective assessment of the ECG at the moment critical decisions are made.”

Queen of Hearts received FDA De Novo authorization in September 2026, establishing a new device classification for AI ECG models targeting acute, life-threatening cardiovascular diagnoses, following FDA Breakthrough Device Designation in March 2025.

“A patient having a heart attack in a rural community deserves the same diagnostic support as one who walks into a major cardiac center,” said Michal Martonak, commercial director at Powerful Medical. “Since FDA authorization, hundreds of health systems and clinical sites across the United States have expressed interest in deploying Queen of Hearts. Tanner is the first to turn that demand into a live deployment across ambulances, emergency departments and the cath lab. It is a blueprint for bringing AI-supported cardiac diagnostics to the point of first medical contact.”

About Powerful Medical
Powerful Medical is leading the AI revolution in cardiology, making expert-level cardiac diagnosis available to every patient, regardless of where they present. Its platform, PMcardio, embeds AI ECG models that interpret 12-lead ECGs to detect acute heart attacks (Queen of Hearts), heart failure, structural heart disease and 40+ other cardiac conditions. PMcardio is used by more than 100,000 clinicians across hospitals, EMS and cardiac centers worldwide.

PMcardio is used more than 2 million times per year, by more than 100,000 clinicians and connects EMS, emergency departments and cardiology teams into a single care coordination platform. Founded in 2019, Powerful Medical has been recognized by awards from Google for Startups, the American Heart Association, Forbes 30 Under 30, the European Innovation Council and as the 2025 MedTech Innovator Accelerator.

About Tanner Health
Tanner Health is a five-hospital non-profit health system providing convenient, personalized healthcare to communities across west Georgia and east Alabama. Tanner Health physicians and staff provide the latest technology and treatment options to advance the health of its patients. In addition to its regional hospitals and care centers, Tanner operates Tanner Medical Group, one of metro Atlanta’s largest multi-specialty physician groups. Learn more at tanner.org.

About Healthliant Ventures
Healthliant Ventures was born out of the idea of Tanner Health being a strategic partner to healthcare startups seeking to validate their products or services, expand their offerings through co-development and market them to other health systems and types of customers. Healthliant Ventures is dedicated to driving innovation, fostering strategic partnerships and transforming the way healthcare is delivered. Committed to advancing the industry, Healthliant Ventures focuses on developing innovative technologies and driving impactful change across the healthcare landscape. Learn more at healthliant.com.