Ncardia Launches Ncyte® Microglia to Advance Research in Neurodegenerative Diseases

LEIDEN, Netherlands--(BUSINESS WIRE)--Ncardia, a global leader in human induced pluripotent stem cell (hiPSC) technology, today announced the launch of Ncyte® Microglia, a groundbreaking tool to advance research in neurodegenerative diseases and central nervous system (CNS) disorders.

Ncyte® Microglia are hiPSC-derived models that closely mimic primary human microglia, exhibiting key functional characteristics such as phagocytosis, cytokine signaling response, and the expression of microglial markers including IBA1, TREM2, and TMEM119. These features make Ncyte® Microglia highly suitable for studying microglial behavior in disease-relevant contexts, assessing immune responses, and enabling high-throughput drug screening applications.

Microglia, the brain’s resident immune cells, play a pivotal role in maintaining CNS health. They are responsible for immune surveillance, mediating inflammation, supporting neuronal development, and participating in synaptic pruning. In addition, dysregulation of microglia is increasingly recognized as a key factor in the pathology of several neurodegenerative diseases, including Alzheimer’s disease (AD), Amyotrophic Lateral Sclerosis (ALS), and Parkinson’s disease (PD). As a result, they have become a crucial focus of neurological research and drug discovery.

“The introduction of Ncyte® Microglia is a significant step forward in providing human-relevant models for CNS research,” said Jeroen de Groot, Divisional CEO of Ncardia. “By offering researchers reliable, scalable, and functionally relevant microglia, we aim to accelerate the discovery of novel therapies for devastating neurological diseases.”

Ncardia continues to drive innovation in iPSC-based technologies, delivering solutions that enhance the predictive power of preclinical models and support the development of safer, more effective treatments for patients worldwide.

For more information about Ncyte® Microglia and Ncardia’s complete portfolio of products and services, please visit www.ncardia.com

About Ncardia

Ncardia is a research and development human iPSC technology company with facilities and offices located throughout Europe and North America. Ncardia is built on the belief that stem cell technology will help bring better therapies to patients faster. The company’s goal is to enable biopharmaceutical companies to accelerate the discovery and development of new therapeutics in any drug modality, including drug, cell, and gene therapy, through the efficient integration of human iPSC technologies.