-

Fierce Biotech Names Synthekine as One of Its “Fierce 15” Biotech Companies of 2022

MENLO PARK, Calif.--(BUSINESS WIRE)--Synthekine Inc., an engineered cytokine therapeutics company, today announced that Fierce Biotech has named it as one of 2022’s Fierce 15 biotechnology companies, designating it as one of the most promising early-stage biotechnology companies in the industry.

“We are honored to be recognized as a Fierce 15 company, reflecting the potential of our distinct cytokine engineering platforms to harness the power of cytokine therapeutics,” said Debanjan Ray, Chief Executive Officer of Synthekine. “I am particularly proud of the substantial progress our talented and dedicated team has made in the three years since Synthekine was founded. Looking ahead, we are eager to build upon the momentum of our maturing pipeline and continue to advance novel cytokine science for the benefit of patients with debilitating cancers and inflammatory diseases.”

Synthekine recently moved STK-012, its IL-2 partial agonist, into clinical investigation and secured its first pharmaceutical partnership on its novel surrogate cytokine agonist platform. The company anticipates entering the clinic later this year with its second program, STK-009 + SYNCAR-001, to address key limitations of current CD19 CAR-T cell therapies.

The Fierce 15 celebrates the spirit of being “fierce” – championing innovation and creativity, even in the face of intense competition. This is Fierce Biotech’s 20th annual Fierce 15 selection.

An internationally recognized daily report reaching a network of over 450,000 biotech and pharma industry professionals, Fierce Biotech provides subscribers with an authoritative analysis of the day's top stories. Every year Fierce Biotech evaluates hundreds of early-stage companies from around the world for its annual Fierce 15 list, which is based on a variety of factors such as the strength of its technology, partnerships, venture backers and a competitive market position.

About Fierce Biotech

Fierce Biotech is the biotech industry's daily monitor, an email newsletter and web resource providing the latest biotech news, articles, and resources related to clinical trials, drug discovery, FDA approval, FDA regulation, patent news, pharma news, biotech company news and more. More than 450,000 top biotech professionals rely on Fierce Biotech for an insider briefing on the day's top stories. Signup is free at www.fiercebiotech.com/signup.

About Synthekine

Synthekine is harnessing the potential of cytokine therapeutics to develop selective immunotherapies designed to improve the treatment paradigm of cancer and inflammatory disease. Using insights on cytokine structure and function, the company engineers therapeutics designed to unlock the full efficacy potential of cytokines while avoiding their associated toxicities. Synthekine is applying principles of cytokine partial agonism and immunological specificity across multiple protein engineering platforms to create a broad and deep pipeline of product candidates. These novel immunotherapies include modified cytokines, cytokine-enhanced cell therapies and surrogate cytokine agonists. For more information, visit www.www.synthekine.com, and follow us on Twitter @synthekine and LinkedIn.

Contacts

Will Zasadny
Evoke Canale
619-961-8848
will.zasadny@evokegroup.com

Rebecca Willumson
Fierce Biotech
202-824-5050
rwillumson@questex.com

Synthekine Inc.


Release Summary
Fierce Biotech names Synthekine as one of its “Fierce 15” Biotech Companies of 2022
Release Versions

Contacts

Will Zasadny
Evoke Canale
619-961-8848
will.zasadny@evokegroup.com

Rebecca Willumson
Fierce Biotech
202-824-5050
rwillumson@questex.com

Social Media Profiles
More News From Synthekine Inc.

Synthekine Presents Updated Clinical and Translational Data Demonstrating Strong Activity for STK‑012 in First‑Line Non‑Squamous NSCLC in Oral Presentation at AACR 2026

MENLO PARK, Calif.--(BUSINESS WIRE)--Synthekine, Inc., a clinical‑stage biotechnology company developing precision cytokine therapeutics, today reported updated clinical and translational data for STK‑012 in combination with pembrolizumab, pemetrexed, and carboplatin (PCT) in first‑line PD‑L1-negative, non‑squamous (NSQ) non‑small cell lung cancer (NSCLC). The data were presented by Salman Punekar, M.D. (NYU Langone Health), in an oral presentation at the American Association for Cancer Researc...

Synthekine Announces AACR 2026 Oral Presentation of Updated Phase 1a/1b Clinical and Translational Data for STK‑012 in First‑Line Nonsquamous NSCLC with Features of Immunotherapy Resistance

MENLO PARK, Calif.--(BUSINESS WIRE)--Synthekine Inc., an engineered cytokine therapeutics company, today announced that updated clinical and translational data from a Phase 1a/1b clinical trial of its α/β biased IL-2 partial agonist, STK-012, will be presented in an oral presentation at the upcoming American Association for Cancer Research (AACR) Annual Meeting 2026 taking place in San Diego, CA from April 17 - 22, 2026. In this now fully enrolled study, STK-012 is being evaluated in combinatio...

Synthekine Announces Clinical Trial Collaboration with Merck to Evaluate STK-012 In Combination with Keytruda® (Pembrolizumab) and Chemotherapy in Ongoing Randomized Phase 2 Trial in First-Line, PD-L1 Negative Nonsquamous Non-Small Cell Lung Cancer

MENLO PARK, Calif.--(BUSINESS WIRE)--Synthekine Inc., an engineered cytokine therapeutics company, today announced that it has entered into a clinical trial collaboration and supply agreement with Merck (known as MSD outside of the United States and Canada). STK-012, a first-in-class α/β-IL-2 receptor biased partial agonist, will be evaluated in combination with standard of care chemotherapy and Keytruda® (pembrolizumab), Merck’s anti-PD-1 (programmed cell death receptor-1) therapy, in the ongo...
Back to Newsroom