Vizgen Showcases Expansion of MERSCOPE™ In Situ Single-Cell Spatial Genomics Platform Capabilities at AGBT

Launch of Human FFPE Immuno-oncology Data Release represents largest public data set for single-cell spatial genomics ever released

Oral and poster presentations highlight how MERSCOPE enables researchers to uncover new findings in the human tumor microenvironment as well as the mouse brain

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Vizgen, the life science company dedicated to improving human health by visualizing single-cell spatial genomics information, today announced an expansion of its product roadmap and the availability of the Formalin-Fixed Paraffin-Embedded (FFPE) Human Immuno-oncology data release. Vizgen’s product updates will expand sample input flexibility, propel new applications, and empower greater data insights. These updates demonstrate the company’s continued commitment to exposing the research community to the power of spatial genomics. The updates will be presented as oral and poster presentations at the Advances in Genome Biology and Technology (AGBT) 2022 General Meeting, occurring June 6-9, 2022.

Product roadmap updates for 2H 2022:

• Formalin-Fixed Paraffin-Embedded Sample Preparation Solution enabling MERFISH measurements on FFPE tissue samples.
• Protein Co-detection Kit for the simultaneous detection of RNA and proteins during a standard MERFISH experiment, enabling multi-omics measurements.
• 1,000 Plex Gene Panels for the detection of up to 1,000 gene targets within a single MERFISH experiment, resulting in higher gene target coverage which is crucial when performing initial discovery experiments.

The new publicly available FFPE Human Immuno-oncology dataset, generated with Vizgen’s MERSCOPE platform, represents the largest public data set for single-cell spatial genomics ever released. This data was generated using Vizgen’s forthcoming FFPE Sample Preparation Kit. The dataset contains 16 total datasets from 8 FFPE tumor tissue types including breast, colon, lung, liver, skin, prostate, uterine and ovarian, each measuring 500 genes totaling over 4 billion transcripts and 9 million cells cumulatively. The dataset is freely available to participants in the company’s Data Release Program to use in any way and can be downloaded at https://info.vizgen.com/merscope-ffpe-solution.

“We announced MERSCOPE, the industry’s first solution to combine single-cell and spatial transcriptomics in one turnkey system, and the only commercial platform solution for MERFISH technology, last year at AGBT. Customer adoption from academic research institutions and pharmaceutical companies has been tremendous and our platform continues to lead spatial genomics innovation in the industry,” said Terry Lo, President and CEO of Vizgen. “With this first of its kind data release, the research community now has access to an unprecedented scale and quality of single-cell spatial genomics data from cancer samples. As we look to establish new standards in the field, we are excited about our upcoming roadmap of new capabilities that further our mission to improve human health.”

AGBT Presentation Details

Date:	Tuesday, June 7, 1:30 p.m. – 3:00 p.m. ET
Title:	In Situ Single-Cell Transcriptomic Imaging in Formalin-Fixed Paraffin-Embedded (FFPE) Tissues with MERSCOPE
Presented by:	Jiang He, Scientific Co-founder, Director of Scientific Affairs, Vizgen
Poster Number:	593
Location:	Bonnet Creek Ballroom Salon VII - XII

Date:	Wednesday, June 8, 8:10 p.m. – 8:30 p.m. ET
Title:	Molecular atlassing with MERSCOPE™: A new spatial transcriptomics technique accurately reveals the organization of the mouse brain transcriptome
Presented by:	George Emanuel, Scientific Co-founder, Director of Technology & Partnerships, Vizgen
Location:	Floridian Ballroom

Vizgen is also proud to sponsor the AGBT Women’s Networking Event, taking place on June 7 from 5:30 – 7:15 p.m. ET.

For additional information about Vizgen’s Human FFPE Immuno-oncology Data Release, visit: https://vizgen.com/human-ffpe-immunooncology-release-roadmap/

About Vizgen

Vizgen is dedicated to pioneering the next generation of genomics, providing tools that demonstrate the possibilities of in situ single-cell spatial genomics, setting the standard for the spatial genomics field. These tools are enabling researchers to gain new insight into the biological systems that govern human health and disease with spatial context. The company’s MERSCOPE™ Platform enables massively multiplexed, genome-scale nucleic acid imaging with high accuracy and unrivaled detection efficiency at subcellular resolution. MERSCOPE provides transformative insight into a wide range of tissue-scale basic research and translational medicine in oncology, immunology, neuroscience, infectious disease, developmental biology, cell and gene therapy, and is an essential tool for accelerating drug discovery and development. For more information, go to www.vizgen.com. Connect on social media Twitter, LinkedIn and Facebook.