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Sonesitatug vedotin reduced the risk of death by 42% in 2nd and later-line CLDN18.2-positive advanced gastric/GEJ cancers in CLARITY-Gastric01

WILMINGTON, Del.--(BUSINESS WIRE)--Positive results from the CLARITY-Gastric01 global Phase III trial showed AstraZeneca’s sonesitatug vedotin (Sone-Ve) demonstrated a statistically significant and highly clinically meaningful improvement in overall survival (OS) in 2nd- and later-line Claudin 18.2-positive advanced gastric cancers versus investigator’s choice of therapy. The trial included patients with locally advanced or metastatic gastric cancer, gastroesophageal junction (GEJ) cancer, or e...
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Genentech’s Divarasib Demonstrated Best-in-Class Efficacy, Advancing the Standard of Care in Previously Treated KRAS G12C-mutated Lung Cancer

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Divarasib demonstrated best-in-class efficacy in Phase III trial, advancing the standard of care in previously treated KRAS G12C-mutated lung cancer...
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TAGRISSO® (osimertinib) plus savolitinib reduced the risk of disease progression or death by 45% and the risk of death by 32% in MET-driven EGFR-mutated lung cancer after progression on TAGRISSO

WILMINGTON, Del.--(BUSINESS WIRE)--Positive results from the SAFFRON Phase III trial showed TAGRISSO® (osimertinib) plus savolitinib demonstrated a statistically significant and clinically meaningful improvement in both progression-free survival (PFS) and overall survival (OS) versus doublet platinum-based chemotherapy in patients with epidermal growth factor receptor-mutated (EGFRm) non-small cell lung cancer (NSCLC). Patients in the trial had tumors with high levels of MET overexpression or a...
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HIMS Deadline: Rosen Law Firm Urges Hims & Hers Health, Inc. (NYSE: HIMS) Stockholders to Contact the Firm for Information About Their Rights

NEW YORK--(BUSINESS WIRE)--Rosen Law Firm, a global investor rights law firm, reminds investors about a class action on behalf of purchasers of securities of Hims & Hers Health, Inc. (NYSE: HIMS) between August 4, 2025 and July 29, 2026. Hims describes itself as a company that “operates a health and wellness platform that connects consumers to licensed healthcare professionals.”For more information, submit a form, email attorney Phillip Kim, or give us a call at 866-767-3653.The Allegations:...
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Agenus Reports 72% of Patients with Locally Advanced dMMR Colon Cancer Had No Cancer Remaining at Surgery Following Six Weeks of BOT+BAL in Phase 2 NEOASIS Study at ESMO 2026

LEXINGTON, Mass.--(BUSINESS WIRE)--Agenus Inc. (Nasdaq: AGEN), a leader in immuno-oncology innovation, today announced early Phase 2 results from the mismatch repair-deficient (dMMR) colon cancer cohort of NEOASIS, an investigator-initiated pan-tumor study sponsored by the Netherlands Cancer Institute (NKI). NEOASIS is evaluating botensilimab (BOT), Agenus’ multifunctional, Fc-enhanced anti-CTLA-4 antibody, in combination with balstilimab (BAL), Agenus’ anti-PD-1 antibody, given before surgery...
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Genmab Announces Updated Follow-Up Analyses from Phase 2 Study of Petosemtamab Demonstrate Meaningful Objective Response Rates in Patients with Metastatic Colorectal Cancer

COPENHAGEN, Denmark--(BUSINESS WIRE)--Genmab A/S (Nasdaq: GMAB) today announced updated follow-up analyses from a Phase 2 trial evaluating petosemtamab, an investigational IgG1-bispecific antibody targeting the epidermal growth factor receptor (EGFR) and leucine-rich repeat containing G-protein-coupled receptor 5 (LGR5), in combination with FOLFOX or FOLFIRI in patients with metastatic colorectal cancer (mCRC). At a median follow-up of 5.9 months in the first-line (1L) setting and 7.1 months in...
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BeOne、「ESMO 2026」で難治性肝がん・肺がんに関する説得力のあるデータを発表

カリフォルニア州サンカルロス--(BUSINESS WIRE)--（ビジネスワイヤ） -- BeOne Medicines Ltd.（Nasdaq：ONC、HKEX：06160、SSE：688235）は、グローバルなオンコロジー企業であり、重点を置く固形腫瘍領域で開発する複数の差別化された治験薬について、「欧州臨床腫瘍学会（ESMO）2026年大会」（10月23～27日、マドリード）で新たなデータを発表しました。発表は消化器がん、肺がん、乳がんに及び、BeOneの固形腫瘍事業が勢いを増していることを示しています。 BeOneの固形腫瘍部門最高医学責任者であるマーク・ラナサ医学博士・哲学博士は、次のように述べています。 「ESMOでは、疾患の生物学的特性に応じて適切なモダリティーを選択するという当社の戦略が、意義ある臨床的進展につながっていることを示しています。当社のGPC3×4-1BB二重特異性抗体は、前治療歴の多い肝細胞がん（HCC）患者において、より長期の追跡でも引き続き良好な忍容性を示し、持続的な活性が認められています。また、当社の脳透過性PRMT5阻害薬とCEA標的ADCの初...
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BeOne Medicines報告TEVIMBRA聯合ZIIHERA在一線HER2陽性胃食管癌中持續帶來生存獲益

加州聖卡洛斯--(BUSINESS WIRE)--(美國商業資訊)-- 全球性腫瘤公司BeOne Medicines Ltd. (Nasdaq: ONC; HKEX: 06160; SSE: 688235)今日公布了HERIZON-GEA-01第三期試驗計畫內的第二次期中分析(IA2)及最終正式分析的最新生存結果，進一步證實TEVIMBRA® (tislelizumab)聯合ZIIHERA® (zanidatamab)及化療做為HER2陽性局部晚期或移轉性胃食管腺癌(GEA)病患一線治療的獲益。這些結果將於今日在西班牙馬德里舉行的2026年歐洲腫瘤內科學會(ESMO)大會的快速口頭報告環節以最新突破性摘要形式公布(LBA79)。 BeOne實質腫瘤醫療長Mark Lanasa, M.D.博士表示： 「繼今年8月獲得美國核准後，這些更長期的數據進一步證實TEVIMBRA聯合ZIIHERA及化療可做為所有一線HER2陽性晚期胃食管腺癌病患的新基準治療方案，無論PD-L1狀態如何。相較於trastuzumab聯合化療，TEVIMBRA聯合ZIIHERA及化療此前所展現的生存獲益幅度在更長隨訪...
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Xencor Presents Phase 1 Dose Selection Data for XmAb819, a Potential First-in-Class ENPP3 x CD3 Bispecific T-Cell Engager, in Development for Patients With Advanced Clear Cell Renal Cell Carcinoma and ENPP3+ Tumors

PASADENA, Calif.--(BUSINESS WIRE)--Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases, today announced updated results from the Phase 1 study of XmAb819, an ENPP3 x CD3 T-cell engaging bispecific antibody, in patients with advanced clear cell renal cell carcinoma (ccRCC). The results were presented by Sumanta Pal, M.D., FASCO, professor and vice chair of academic affairs at City of Hope Comp...
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Frontier Medicines Presents Promising Anti-Tumor Activity from Phase 1/2 PROSPER Trial of FMC-376 in a Highly Resistant Patient Population of KRAS G12C-Mutant NSCLC at ESMO 2026

BOSTON & SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Frontier Medicines Corporation, a clinical-stage precision medicines company unlocking the proteome to develop small molecule oncology and immunology drugs against previously undruggable disease-causing targets, today announced promising preliminary clinical data from the ongoing Phase 1 monotherapy portion of its Phase 1/2 PROSPER trial evaluating FMC-376, a KRAS G12C ON+OFF inhibitor, in patients with advanced KRAS G12C-mutant solid tumor...