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アジーナス、Nature Medicine掲載の多施設共同第2相UNICORN試験論文を発表、切除可能な結腸がんに対する術前BOT+BALで深い奏効を実証

マサチューセッツ州レキシントン--(BUSINESS WIRE)--(ビジネスワイヤ) -- アジーナス(Agenus Inc.)(Nasdaq:AGEN)は、免疫腫瘍学のイノベーションをリードする企業で、切除可能な局所進行結腸がん患者を対象に、アジーナスの多機能性Fc強化型抗CTLA-4抗体ボテンシリマブ(BOT)を単独または同社の抗PD-1抗体バルスチリマブ(BAL)との併用で短期術前(ネオアジュバント)投与する研究者主導・多施設共同第2相UNICORN試験の結果が、査読付き論文として掲載されたと発表しました。論文「切除可能な局所進行pMMRまたはdMMR結腸がん患者に対するバルスチリマブ併用または非併用の術前ボテンシリマブ:GONOによるUNICORN試験」はNature Medicineに掲載され、DOI 10.1038/s41591-026-04710-1で閲覧できます。 UNICORN試験には56人が登録され、各14人からなる4つの非無作為化コホートで、ミスマッチ修復機能正常/マイクロサテライト安定性(pMMR/MSS)およびミスマッチ修復機能欠損/高頻度マイクロサテライ...
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Deadline Alert: Yiren Digital Ltd. Shareholders Have Until December 28, 2026 to Seek Lead Plaintiff Appointment in Securities Fraud Lawsuit, The Law Offices of Frank R. Cruz Notes

LOS ANGELES--(BUSINESS WIRE)--The deadline for Yiren Digital Ltd. ("Yiren" or the "Company") (NYSE: YRD) investors to seek appointment as lead plaintiff in a securities class action lawsuit is December 28, 2026. The lawsuit was filed on behalf of investors who purchased or otherwise acquired Yiren Digital Ltd. securities from April 29, 2026 to October 13, 2026, inclusive. The Law Offices of Frank R. Cruz today reminded investors of the deadline in the case, Lester et al v. Yiren Digital Ltd. et...
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Gencom Acquires Rosewood London, Expanding Its Footprint With Its First Luxury Hotel Acquisition in Europe

MIAMI--(BUSINESS WIRE)--Gencom, a U.S.-based investment firm that owns and develops prized real estate around the world, announces the acquisition of Rosewood London, the landmark 308-key luxury hotel situated at 252 High Holborn in Central London. The acquisition strengthens Gencom’s global hospitality investment platform and expands its presence in Europe through its first luxury hotel asset in London. London is one of the world’s most supply-constrained hospitality markets, supported by year...
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Inszone Insurance Services Acquires Whitman & Samuelson Insurance Services, Expanding Its Commercial Manufacturing and Distribution Expertise in Northern California

SACRAMENTO, Calif.--(BUSINESS WIRE)--Inszone Insurance Services, a rapidly growing national provider of commercial, personal, and benefits insurance, is pleased to announce the acquisition of Whitman & Samuelson Insurance Services, Inc. This acquisition expands Inszone's commercial lines presence in Northern California, welcoming a nearly century-old agency with deep, specialized expertise in commercial manufacturing and distribution. With roots dating back to 1931 and based in Petaluma, Ca...
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Deadline Alert: UP Fintech Holding Limited Stockholders Face December 28, 2026 Lead Plaintiff Deadline in Securities Fraud Class Action, The Law Offices of Howard G. Smith Highlights

BENSALEM, Pa.--(BUSINESS WIRE)--UP Fintech Holding Limited ("UP Fintech" or the "Company") (NASDAQ: TIGR) investors who wish to serve as lead plaintiff in a pending securities fraud class action lawsuit must move the Court by December 28, 2026. The suit was filed on behalf of investors who purchased or otherwise acquired the Company's securities from April 22, 2024 through June 2, 2026, inclusive. The Law Offices of Howard G. Smith today highlighted the deadline in the case, Liao v. Up Fintech H...
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Lubrizol Earns EcoVadis Gold, Reinforcing Sustainability Progress and Customer Partnerships

CLEVELAND--(BUSINESS WIRE)--Lubrizol earned an EcoVadis Gold Medal, placing the organization among the top 5% of companies assessed by EcoVadis across all industries worldwide in the 12 months preceding its scorecard publication. For customers who use EcoVadis to evaluate suppliers, the assessment provides independent evidence of Lubrizol’s sustainability management system to support supplier evaluations and responsible sourcing. The distinction marks another milestone in the company’s continue...
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Seismic and Highspot by Seismic Each Named a Leader in 2026 Gartner® Magic Quadrant™ for Revenue Enablement Platforms

SAN DIEGO--(BUSINESS WIRE)--Both the Seismic and Highspot by Seismic platforms have been named a Leader in the 2026 Gartner® Magic Quadrant™ for Revenue Enablement Platforms....
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Elgi Equipments Introduces Patented Demand=Match™ Technology to the Middle East and Africa at Gulfood Manufacturing 2026

DUBAI, United Arab Emirates--(BUSINESS WIRE)--Elgi Equipments today announced the launch of its patented ELGi Demand=Match™ technology in the Middle East and Africa at Gulfood Manufacturing 2026....
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TotalEnergies SE UK Regulatory Announcement: Director/PDMR Shareholding

PARIS--(BUSINESS WIRE)--  Notification and Public Disclosure of transactions by Persons Discharging Managerial Responsibilities Paris, November 3rd, 2026 - TotalEnergies SE has received a notification of dealing from a Person Discharging Managerial Responsibilities (“PDMR”). The notification of dealing form can be found below. This notification is made in accordance with the UK Market Abuse Regulation. ____ About TotalEnergies TotalEnergies is a global integrated energy company that produces an...
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ICAPE - Chiffre d’affaires de 68,7 M€ au T3 2026 : +36,4% yoy et +34,2% en organique à change constant

FONTENAY-AUX-ROSES, France--(BUSINESS WIRE)--Regulatory News: Le Groupe ICAPE (code ISIN : FR001400A3Q3 – mnémonique : ALICA), distributeur technologique mondial de cartes de circuits imprimés (« PCB ») et de pièces électromécaniques à façon, annonce aujourd’hui son chiffre d’affaires pour le 3ème trimestre et les 9 premiers mois de 2026. Yann DUIGOU, Directeur Général du Groupe ICAPE, déclare : « Le troisième trimestre 2026 marque une nouvelle accélération de notre croissance, à +36,4% après +...