Medable and ICON Exceed Patient eConsent Adoption Goals for Women’s Health Study on Menopause

Over 85% of patients consented electronically using Medable’s Total Consent solution

PALO ALTO, Calif.--(BUSINESS WIRE)--Medable Inc., the leading technology platform for agentic AI clinical development, today announced the impact of its Total Consent solution in a U.S women’s health study on menopause managed by ICON plc. Beating expectations, more than 85% of trial participants, or 1,044 out of 1,222, consented using Medable’s enhanced eConsent technology. And, 18 sites achieved 100% eConsent adoption among participants, while the top-enrolling site achieved 91% adoption. With Medable, ICON aims to expand its use of advanced clinical trial technologies, reflecting broader momentum across the clinical research ecosystem, including the FDA, toward more real-time and technology-enabled trials.

With a protocol requiring regular assessments across 13 points, ICON’s menopause study demanded high participant and site engagement from the outset. Medable’s Total Consent proved instrumental in engagement with improved participant communication. Study-specific training plus hands-on concierge support to sites helped enable a frictionless experience. The strategy yielded significant success in both participant and site-level adoption of consent, laying the groundwork for increased patient adherence to the complex protocol requirements.

“Thanks to a strong partnership with ICON and our deep-domain expertise, we were able to achieve remarkable enrollment goals,” said Alison Holland, Medable’s Chief Customer Officer. “Remote electronic consent is particularly beneficial to driving female participation due to increased time constraints for women and mothers juggling family care responsibilities. But all trials can benefit from modern trial design. Medable aims to radically reduce trial timelines in line with our 1:1:1 mission – 1 day study start, 1 day enrollment, 1 year trial execution.”

Medable Total Consent allows participants to consent onsite or remotely, with eSignature or wet ink signature, increasing patient satisfaction by providing optionality. It can be quickly tailored for use across over 115 locales in compliance with local regulatory requirements. Most recently, Medable introduced Intelligent Consent, providing AI-powered bulk processing and AI-assisted digital consent build tools that leverage native PDFs. The product’s unified workflow reduces deployment time from 5-14 days to less than three days.

The successful ICON study results provide real-world context for an eConsent study by Medable and Duke BASE labs that compared Total Consent against text-only eConsent across 24 patients and found 71% of patients preferred the enhanced solution, saying it made the process more engaging, informative, and humanized. Another study of the consenting process of 35 clinical trials (representing 13,200+ participants) found patients using eConsent versus paper had a better understanding of the trial information.

Learn more about the ICON study here or contact Medable.

About Medable

Medable is on a mission to get effective therapies to people faster. Its agentic clinical trials platform enhances speed, scale, and patient access in clinical research, accelerating medicines for thousands of conditions without treatment or cure. Awarded Leader in eCOA by Everest Group, Medable’s platform has been deployed in nearly 400 trials in 70 countries and 120 languages, serving more than one million patients globally. Medable is a privately held, venture-backed company headquartered in Palo Alto, California. Learn more at medable.com.