Atropos Health and Guidehouse Launch Point-of-Care Clinical Decision Support Solution for Life Sciences

EHR-embedded predictive analytics help life sciences companies translate real-world evidence into action at the moment of care for healthcare teams

PALO ALTO, Calif. & MCLEAN, Va.--(BUSINESS WIRE)--Atropos Health, the world’s largest creator of real-world evidence (RWE) for clinical decision making, and Guidehouse, a global professional services firm serving the commercial and government sectors, have launched a jointly developed clinical decision support (CDS) solution designed to operationalize RWE directly within clinical workflows.

The CDS solution combines Atropos Health’s predictive modeling and evidence generation capabilities with Guidehouse’s expertise in commercialization, medical strategy, and market access to help life sciences organizations translate insight into action at the point of care.

The joint solution delivers an end-to-end, closed-loop approach to CDS, spanning model design, validation, deployment, and measurement. Built on predictive algorithms using real-world data, it embeds evidence-based insights directly into the electronic health record (EHR), enabling healthcare teams to identify relevant patients and make informed diagnosis and treatment decisions.

"Partnering with Guidehouse marks a pivotal moment in our mission to bring real-world evidence to the forefront of clinical and commercial decision making,” said Dr. Brigham Hyde, CEO and co-founder of Atropos Health. “Together, we can deliver AI-driven insights at a scale and speed the pharmaceutical industry has never seen before—helping get the right treatments to the right patients faster, with a goal to ultimately save lives."

Using aggregated claims and EHR data, the predictive models stratify patient populations, identify under or undiagnosed patients, and surface treatment considerations tailored to individual patients. Outputs are delivered as in‑workflow alerts and insights within the EHR, supporting timely interventions such as screening, referral, or treatment optimization while minimizing disruption to provider workflows.

For life sciences organizations, the solution is designed to bridge the persistent gap between evidence generation and real‑world impact. By pairing EHR‑embedded clinical insights with a structured dissemination and measurement approach, it supports compliant commercial and medical strategies, while providing field teams with insights into treatment patterns and care dynamics that inform more effective engagement.

The CDS solution helps life sciences organizations:

• Translate predictive analytics into clear, in‑workflow actions at the point of care
• Enable healthcare teams to identify patients who may be underdiagnosed, undertreated, or at risk of suboptimal outcomes
• Support earlier and more appropriate treatment decisions through validated real-world evidence
• Inform compliant customer engagement strategies across pharmaceutical market access and medical teams to drive optimal treatment choices and care pathways

“Our CDS solution reflects a shift from insight generation to insight deployment,” said Jacob Graham, Partner, Life Sciences, at Guidehouse. “By combining Atropos Health’s predictive modeling and evidence capabilities with Guidehouse’s experience operationalizing solutions in the market, we are helping clients embed real‑world evidence into care delivery in a way that drives measurable clinical and commercial impact.”

About Atropos Health

Atropos Health is closing medicine's most consequential gap: actionable evidence to inform the vast majority of clinical decisions that are made without evidence. By generating real-world evidence from actual patient outcomes and data, Atropos Health is building the evidence infrastructure that clinicians, life science researchers and AI platforms need to practice, develop and inform medicine, grounded in what actually works. Better healthcare is only possible with evidence, and Atropos Health is working to make it available for every patient, in every healthcare decision, every day. Atropos Health does this via GENEVA OS®, the operating system across a robust network of real-world data; Alexandria, the world’s largest evidence library; and evidence generation tools such as ChatRWD®, Green Button® and the Atropos Evidence™ Agent. To learn more about Atropos Health, visit www.atroposhealth.com or connect through LinkedIn or X (Twitter).

About Guidehouse

Guidehouse is a global professional services firm delivering advisory, technology, and managed services to the commercial and government sectors. With an integrated business technology approach, Guidehouse drives efficiency and resilience in the healthcare, financial services, energy, infrastructure, and national security markets. Built to help clients across industries outwit complexity, the firm brings together approximately 18,000 professionals to achieve lasting impact and shape a meaningful future. guidehouse.com