-

Vaxess Technologies Awarded NSF and DARPA Funding for Development of mRNA-Based Single-Dose, Refrigeration-Free Vaccine Patch

Funding will advance development of single-dose mRNA vaccines and other medical countermeasures able to bypass the cold-chain in a painless patch format

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Vaxess Technologies, Inc., an innovative biotechnology company developing the MIMIX™ smart release patch, was awarded a grant from the National Science Foundation (NSF award number 2030305) and a subcontract from the Defense Advanced Research Projects Agency (DARPA), a branch of the US Department of Defense, to advance two separate projects aimed at developing mRNA-based vaccines and other medical countermeasures with the following features:

  • Refrigeration-free, using the patented Silk Protein Matrix stabilization technology
  • Single dose administration, enabled by MIMIX™ sustained release formulation
  • Painless application via MIMIX™ skin patch

Total funding awarded will be up to $2,000,000 if all milestones are achieved, including a $256,000 phase I SBIR grant from the NSF. Vaxess will use the funding to integrate mRNA-based vaccines and gene modulators provided through a collaboration with the Santangelo Lab at Georgia Tech into MIMIX™ patches to improve the efficacy and administration of novel mRNA-based vaccines and other medical countermeasures.

The MIMIX™ platform patch technology provides a solution to challenges related to global vaccine distribution and delivery. The painless patch, which utilizes a patented sustained release technology, is shelf-stable, enables dramatic enhancements in protection, and can be self-applied, allowing greater ease in distribution and administration. Thanks to the Silk Protein Matrix patented technology, the product will not require ultra-cold chain logistics, a critical attribute for timely distribution in times of pandemic outbreaks.

The patch is also compatible with a wide range of COVID-19 vaccine candidates, as demonstrated by Vaxess’ work towards a combination seasonal protection patch that includes both a COVID-19 vaccine and a broadly protective seasonal flu vaccine.

“Funding from the NSF and DARPA represent a renewed commitment from the Federal Government to support the development of novel vaccines to combat the current pandemic and future threats,” said Vaxess co-founder Livio Valenti. “Vaxess will continue to be a source of innovation to address some of the most pressing challenges we are facing today and in the years to come.”

About the MIMIX Smart Release Patch Platform

Medicine delivery, redefined. The MIMIX patch delivers medicines and vaccines through a number of tiny, painless projections that dissolve at a precisely engineered rate, releasing their treatment at its most effective dose for the most beneficial length of time. Vaxess has validated performance and compatibility with a range of molecules including proteins, killed viruses, mRNA, hormones, and live viruses.

More effective medications start with MIMIX. The MIMIX platform dramatically improves efficacy of products across a broad range of therapeutic areas by “mimicking” the prolonged exposure period that occurs during a natural infection. This prolonged exposure triggers a stronger and more enduring immune response for vaccines and immunotherapies.

Seamlessly painless. The MIMIX patch is virtually painless and after wearing it for few minutes, it is removed from the skin while the medication continues to be delivered.

About Vaxess Technologies

Vaxess Technologies is a biotechnology company headquartered in Cambridge, Massachusetts. The company is developing its proprietary sustained release smart delivery technologies to meet the need for more efficacious, refrigeration-free and easy to administer medical products. For more information please visit the company website at www.vaxess.com or send any additional inquiry to contact@vaxess.com.

Contacts

Media:
Danielle Reisley
Vaxess Technologies, Inc.
danielle@vaxess.com

Vaxess Technologies, Inc.


Release Summary
Vaxess Technologies Awarded NSF and DARPA Funding for Development of mRNA-Based Single-Dose, Refrigeration-Free Vaccine Patch
Release Versions

Contacts

Media:
Danielle Reisley
Vaxess Technologies, Inc.
danielle@vaxess.com

More News From Vaxess Technologies, Inc.

Vaxess Announces Production of The First GMP Batch of MIMIX™ Technology Vaccine Patches for an Upcoming Phase 1 Seasonal Influenza Clinical Trial; Clinical Entry Expected This Summer Based on a Successful February Pre-CTA Meeting With Health Canada.

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Vaxess Technologies, Inc., an innovative life sciences company developing a pipeline of shelf-stable and simple-to-apply vaccines on the MIMIX patch platform announced significant progress towards clinical entry for the company’s lead program, MIMIX-Flu. MIMIX-Flu, developed in collaboration with GC Pharma, combines GC’s commercial seasonal influenza vaccine antigen with Vaxess’s innovative MIMIX patch-based intradermal controlled release delivery system. MIMI...

Vaxess Bolsters Commitment To Vaccine Patch Leadership With Purpose-Built Cambridge Lab And Fortified Management Team With The Addition Of A Veteran CFO And Head Of Device Development

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Vaxess Technologies, Inc., an innovative life sciences company developing a pipeline of shelf-stable and simple-to-apply vaccines on the MIMIX patch platform announced occupancy of a second new facility and significant additions to the leadership team. The new Cambridge headquarters will house the company’s administrative and R&D teams as the company expands the development and proofs of concept of vaccines formulated and delivered in Vaxess’s proprietary...

Vaxess Technologies Announces Grand Opening of GMP Manufacturing Facility

WOBURN, Mass.--(BUSINESS WIRE)--Vaxess Technologies, a biotechnology startup developing the MIMIXTM sustained-release intradermal microneedle patch, celebrated the grand opening of their 3,600 square feet pilot GMP (Good Manufacturing Practices) manufacturing facility on Monday. The facility, which is located in Woburn, MA at one of the Cummings Park properties, will feature a state-of-the-art cleanroom where manufacturing of vaccine patches for clinical trials will take place. Using the clinic...
Back to Newsroom