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马萨诸塞州坎顿--(BUSINESS WIRE)--(美国商业资讯)-- Orthogon Therapeutics今日宣布完成1100万美元的后续融资，使其总融资额达到3600万美元。该笔融资将用于支持其首创的BK多瘤病毒药物的持续研发。BK病毒感染是移植患者出现并发症的主要原因之一，目前尚无获批的治疗方法。 该公司正在率先研发一种口服疗法，该疗法能够应对BK病毒感染的各个阶段，从早期复发到全身扩散，直至重症的发生。Orthogon公司通过靶向此前小分子药物难以触及的病毒蛋白，正在其他疗法束手无策的情况下，推进一项新的解决方案。 Orthogon的主要候选药物独特地靶向病毒衣壳蛋白（VP1），在病毒复制部位发挥强效的抗病毒作用。其细胞内活性可对BK病毒各亚型及相关人类多瘤病毒实现持续控制，尤其对移植患者效果显著，在该人群中，病毒持续存在是导致疾病的主要原因。 “ 这并非传统的抗病毒治疗场景。我们启动这一项目正是为了应对器官移植治疗的现实挑战 ，”Orthogon Therapeutics首席执行官Ali H. Munawar博士表示。“ 这些患者的治疗需要在免疫抑制、器官功能与高药物...

THE WOODLANDS, Texas--(BUSINESS WIRE)--Perma-Pipe International Holdings, Inc. (NASDAQ: PPIH) anunció el día de hoy los resultados financieros correspondientes al cuarto trimestre y al ejercicio fiscal 2025, que finalizó el 31 de enero de 2026. "En el trimestre que finalizó el 31 de enero de 2026, las ventas netas ascendieron a USD 55,1 millones, lo que supone un aumento de USD 10,1 millones o un 22,4 %, en comparación con los USD 45,0 millones del mismo trimestre del año anterior. El crecimien...

CHICAGO--(BUSINESS WIRE)--The postponement of Blue Cross Blue Shield of Michigan’s (BCBSM) proposed reimbursement policy affecting evaluation and management (E/M) services billed with modifier 25 marks a critical step in safeguarding accurate physician reimbursement, reducing administrative burden and protecting patient access to timely, high-quality care. The decision, announced April 15, follows significant feedback from osteopathic physicians and organized medicine regarding the policy’s ope...

SEATTLE & LAKE CHARLES, La.--(BUSINESS WIRE)--Saltchuk Marine, LLC and Harbor Docking & Towing (HDT) today announced the formation of Green Tug Towing (GTT), a new joint venture company established to provide towage, escort, and terminal support services in the United States. GTT has been awarded a 20-year services contract by Woodside Energy to design, build, and operate four advanced hybrid escort tugboats to support LNG carrier operations at the company’s new Calcasieu Parish terminal. A...

TORONTO--(BUSINESS WIRE)--Granite Real Estate Investment Trust (“Granite”) (TSX: GRT.UN) announced today that its board of trustees has declared a distribution of CDN $0.2958 per unit for the month of April 2026. The distribution will be paid by Granite on May 15, 2026 to unitholders of record at the close of trading on April 30, 2026. Granite confirms that no portion of the distribution constitutes effectively connected income for U.S. federal tax purposes. A qualified notice providing the bre...

DALLAS--(BUSINESS WIRE)--Celanese Announces Engineered Materials Price Increase...

NEW YORK--(BUSINESS WIRE)--DWS, a leading European asset manager with global reach, today announced the impending closure and liquidation of two Xtrackers ETFs: Xtrackers Risk Managed USD High Yield Strategy ETF (NYSE: HYRM) and Xtrackers California Municipal Bond ETF (NASDAQ: CA). Xtrackers Risk Managed USD High Yield Strategy ETF is listed on NYSE. After the close of business on May 7, 2026, the fund will no longer accept creation orders and will end trading. The fund will accept redemption o...

CANTON, Mass.--(BUSINESS WIRE)--Orthogon Therapeutics maakte vandaag de afronding bekend van een follow-on financiering van $11 miljoen, waarmee het totaal van het opgehaalde kapitaal op $36 miljoen komt. Deze financiering ondersteunt de continue vorderingen van haar uitstekende geneesmiddel tegen het BK-polyomavirus. BK-virusinfecties zijn een belangrijke oorzaak van complicaties bij patiënten die een transplantatie hebben ondergaan, waarvoor geen goedgekeurde behandelingen bestaan. Het bedrij...

HARTFORD, Conn.--(BUSINESS WIRE)--Virtus Dividend, Interest & Premium Strategy Fund (NYSE: NFJ) (the “Fund”) today announced that its Board of Trustees has approved a tender offer (“Tender Offer”) intended to enhance shareholder value, provide shareholders with an additional source of liquidity for their investment, and provide the potential to reduce the Fund’s trading discount to its net asset value per share (“NAV”). Pursuant to the terms of the Tender Offer, the Fund will offer to purch...

LEWISVILLE, Texas--(BUSINESS WIRE)--Davidson Bogel Real Estate (DB2RE) successfully facilitated the acquisition of an 8.5-acre, four-owner industrial land assemblage located at 421, 451, 475, and 493 Bennett Lane in Lewisville. The site was acquired by Lovett Industrial and is planned for the development of a Class A industrial project. The development aligns with the City of Lewisville’s evolving regulatory framework for industrial uses. The transaction was facilitated by Philip Cherrick of Da...