Doximity Outranks OpenEvidence, Frontier Models in Independent Stanford-Harvard Study of Clinical AI Safety

Doximity Ask outranked OpenEvidence, GPT-5.6 Sol, Claude Fable 5, and other frontier models

SAN FRANCISCO--(BUSINESS WIRE)--Doximity, Inc. (NYSE: DOCS), the leading digital platform for U.S. medical professionals, today announced that Doximity Ask, its HIPAA-compliant clinical AI platform, outperformed leading frontier AI models in the NOHARM (Numerous Options Harm Assessment for Risk in Medicine) benchmark, one of the most comprehensive independent evaluations of clinical AI safety to date.

The study, conducted by ARISE, a clinical AI research team led by physicians from Stanford and Harvard Medical Schools, evaluated how AI models perform when researchers prompted them with simulated patient cases.

Doximity Ask ranked first among all AI systems evaluated on the study's real-world clinical sample, the portion of the benchmark that most closely mirrors how physicians use these tools in practice. Across the broader automated evaluation, purpose-built clinical AI systems outperformed general-purpose frontier models by a wide margin.

Why Doximity Ask Outperformed

Doximity Ask is a HIPAA-compliant AI assistant built specifically for clinical workflows.

Our performance traces directly to our investment in physician authorship at scale. Through our PeerCheck™ program, more than 11,000 cited physician experts have evaluated and improved Doximity Ask outputs.

"We have long believed that the path to trustworthy healthcare AI runs through physicians, not around them," said Dr. Louis-Antoine Mullie, Head of Medical AI at Doximity. "Continuous physician review isn't a differentiator. It's a requirement. This result reinforces the importance of combining advanced AI systems with rigorous clinical oversight and independent safety evaluations like NOHARM."

Doximity's Clinical AI Suite, including Ask, has been reviewed, approved, and deployed across more than 150 health systems, including eight of the nation's top 20 hospitals.

The platform includes end-to-end encryption, role-based access controls, audit logging, and session isolation to help healthcare organizations deploy AI while maintaining enterprise-grade security and privacy standards.

To learn more about Doximity Ask, visit www.doximity.com.

Read more about the study methodology on the Doximity blog.

Notes to Editors:

• For the full study, please click here.
• The chart on the left shows how the top U.S. models performed on F1 score, which balances precision and recall, before the cases and answers were made public.
• The chart on the right shows automated testing across more than 1,100 scenarios spanning 10 medical specialties. The benchmark was developed by more than 50 researchers with contributions from 29 board-certified physicians.

About Doximity

Founded in 2010, Doximity is the leading digital platform for U.S. medical professionals. The company's network members include more than 85% of U.S. physicians across all specialties and practice areas. Doximity provides its verified clinical membership with digital tools built for medicine, enabling them to collaborate with colleagues, stay current on medical news and research, manage their careers and on-call schedules, streamline documentation and administrative paperwork, and conduct virtual patient visits. With new AI-powered clinical reference and search capabilities, Doximity also helps doctors access trusted, peer-reviewed information and medical literature. Doximity's mission is to help doctors be more productive so they can provide better care for their patients.