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ヨルテック・セラピューティクス、α1-アンチトリプシン欠乏症治療用のYOLT-202において良好な中間データを発表

上海--(BUSINESS WIRE)--(ビジネスワイヤ) -- 生体内ゲノム編集療法を開発している臨床後期段階のバイオテクノロジー企業であるヨルテック・セラピューティクスは、α1-アンチトリプシン欠乏症(AATD)の治療を目的とする同社の開発中生体内塩基編集療法YOLT-202について、医師主導治験(IIT)における中間データが良好であることを発表しました。35mgおよび45mgの用量レベルで投与された評価対象患者において、安全性および忍容性が良好であることに加え、AAT値の意義のある上昇が示されました。 「今回の中間結果は、ヨルテックにとっても、重症AATDとともに生きる患者にとっても、重要かつ意義深いマイルストーンとなるものです。本治験で観察された機能的AAT値の迅速かつ力強い、そして用量依存的な上昇は、特にPiZZ遺伝子型を持つ患者において顕著であり、生体内塩基編集が単回投与による治療アプローチとして持つ変革的な可能性を裏付けています」と、ヨルテック・セラピューティクスの創設者兼最高経営責任者(CEO)であるYuxuan Wu医師は述べています。「これまでに確認されている良...
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Telekom Srbija Group Announces Platinum Sponsorship of EXPO 2027 Belgrade

BELGRADE, Serbia--(BUSINESS WIRE)--Telekom Srbija Group today announced its Platinum Sponsorship of EXPO 2027 Belgrade, marking a major milestone in the company’s continued leadership in digital innovation and infrastructure across the region. As a Platinum Sponsor, Telekom Srbija will play a central role in delivering the digital backbone of EXPO 2027, powering connectivity and enabling the state-of-the-art technological infrastructure that will support one of the largest international events...
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AdvanSix Announces Fourth Quarter and Full Year 2025 Financial Results

PARSIPPANY, N.J.--(BUSINESS WIRE)--AdvanSix Announces Fourth Quarter And Full Year 2025 Financial Results...
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NATIXIS UK Regulatory Announcement: Form 8.3

LONDON--(BUSINESS WIRE)--  FORM 8.3 PUBLIC OPENING POSITION DISCLOSURE/DEALING DISCLOSURE BY A PERSON WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE Rule 8.3 of the Takeover Code (the “Code”) 1. KEY INFORMATION (a) Full name of discloser: NATIXIS SA (b) Owner or controller of interests and short positions disclosed, if different from 1(a): The naming of nominee or vehicle companies is insufficient. For a trust, the trustee(s), settlor and beneficiaries must be named.   (c) Name o...
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AngloGold Ashanti Q4 and Year Ended 31 December 2025 Earnings Release and Dividend Declaration

LONDON & DENVER & JOHANNESBURG--(BUSINESS WIRE)--AngloGold Ashanti plc’s(2) delivered record free cash flow*(5) of $2.9bn in 2025 on strong production growth, continued cost discipline and a higher average gold price received per ounce*. The Company announced an interim dividend of $875m for Q4 2025, taking the total payout declared for 2025 to $1.8bn, the highest ever. AngloGold Ashanti again achieved guidance on gold production and sustaining capital expenditure*, as it continues to build a t...
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NATIXIS UK Regulatory Announcement: Form 8.3

LONDON--(BUSINESS WIRE)--  FORM 8.3 PUBLIC OPENING POSITION DISCLOSURE/DEALING DISCLOSURE BY A PERSON WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE Rule 8.3 of the Takeover Code (the “Code”) 1. KEY INFORMATION (a) Full name of discloser: NATIXIS SA (b) Owner or controller of interests and short positions disclosed, if different from 1(a): The naming of nominee or vehicle companies is insufficient. For a trust, the trustee(s), settlor and beneficiaries must be named.   (c) Name o...
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NATIXIS UK Regulatory Announcement: Form 8.3

LONDON--(BUSINESS WIRE)--  FORM 8.3 PUBLIC OPENING POSITION DISCLOSURE/DEALING DISCLOSURE BY A PERSON WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE Rule 8.3 of the Takeover Code (the “Code”) 1. KEY INFORMATION (a) Full name of discloser: NATIXIS SA (b) Owner or controller of interests and short positions disclosed, if different from 1(a): The naming of nominee or vehicle companies is insufficient. For a trust, the trustee(s), settlor and beneficiaries must be named.   (c) Name o...
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Axelspace Secures Japan Ministry of Defense Satellite Constellation Project

TOKYO--(BUSINESS WIRE)--Axelspace Corporation (“Axelspace”), a leading developer and operator of microsatellites dedicated to realizing its vision of “Space within Your Reach,” announced that, for the purpose of carrying out the Ministry of Defense’s satellite constellation project, it has entered into a contract with Tri-Sat Constellation Co., Ltd. and Mitsui Bussan Aerospace Co., Ltd. for acquisition of optical imagery data. Tri-Sat Constellation Co., Ltd. is a special purpose company (SPC) e...
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NATIXIS UK Regulatory Announcement: Form 8.3

LONDON--(BUSINESS WIRE)--  FORM 8.3 PUBLIC OPENING POSITION DISCLOSURE/DEALING DISCLOSURE BY A PERSON WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE Rule 8.3 of the Takeover Code (the “Code”) 1. KEY INFORMATION (a) Full name of discloser: NATIXIS SA (b) Owner or controller of interests and short positions disclosed, if different from 1(a): The naming of nominee or vehicle companies is insufficient. For a trust, the trustee(s), settlor and beneficiaries must be named.   (c) Name o...
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アクセルスペース、防衛省の「衛星コンステレーションの整備・運営等事業」を受注

東京--(BUSINESS WIRE)--(ビジネスワイヤ) -- 小型衛星を開発・運用し、誰もが宇宙を利用できる社会を目指して事業を展開する株式会社アクセルスペース(本社:東京都中央区、代表取締役:中村 友哉、以下「当社」)は、防衛省の「衛星コンステレーションの整備・運営等事業」(以下「本事業」)の実施のため、三菱電機株式会社(本社:東京都千代田区、執行役社長:漆間 啓)、スカパーJSAT株式会社(本社:東京都港区、代表取締役 執行役員社長:米倉 英一)、三井物産株式会社(本社:東京都千代田区、社長:堀 健一)により設立された特別目的会社、株式会社トライサット・コンステレーション(本社:東京都新宿区、代表取締役Co-CEO:大藤 英之、森合 裕)及び三井物産エアロスペース株式会社(本社:東京都千代田区、代表取締役社長:青木 盛博)と、光学衛星画像の納入に係る衛星画像データ取得業務等委託契約を締結したことをお知らせいたします。 本事業について、当社は株式会社トライサット・コンステレーションを構成する3社、株式会社Synspective(本社:東京都江東区、代表取締役CEO:新井 元行...