Flex Pharma, Inc. (NASDAQ: FLKS), a biotechnology company developing innovative and proprietary treatments for spasms associated with severe neuromuscular conditions, nocturnal leg cramps and exercise-associated muscle cramps, announced today that it will present at the 26th International Symposium on amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND) in Orlando, FL on Saturday, December 12th at 6:40pm ET.
Data demonstrating GMP-synthesized single agent efficacy in significantly reducing human muscle cramp intensity in its electrically induced cramp model will be presented in the abstract titled “TRPV1 and TRPA1 Activators Reduce Muscle Cramping. Potential New Treatment For ALS Symptoms.”
“Local and topical stimulation of TRPA1 and TRPV1 in the mucous membranes by one or two activators is a potentially effective strategy to inhibit cramping,” noted National Academy of Sciences member Dr. Bruce Bean, Professor of Neurobiology at Harvard Medical School, Flex Pharma Scientific Co-Founder and Scientific Advisory Board Co-Chair. He added, “Chemical Neuro Stimulation by TRPA1 and TRPV1 activators reduces cramping induced by electrical stimulation, and we are hopeful that this approach might also alleviate cramping and spasms from disorders like ALS and MS.”
Flex Pharma plans to evaluate the effectiveness of single agent drug candidate FLX-787 as a potential treatment for cramps associated with ALS and plans to initiate a study outside the U.S. in the first half of 2016.
About Flex Pharma
Flex Pharma, Inc. is a biotechnology company that is developing innovative and proprietary treatments for spasms associated with severe neuromuscular conditions, nocturnal leg cramps and exercise-associated muscle cramps. In three randomized, blinded, placebo-controlled, cross-over studies, Flex Pharma's proprietary treatment has shown a statistically significant reduction in the intensity of muscle cramps in healthy normal volunteers.
Flex Pharma was founded by National Academy of Sciences members Rod MacKinnon, M.D. (2003 Nobel Laureate), and Bruce Bean, Ph.D., recognized leaders in the fields of ion channels and neurobiology, along with Chairman and Chief Executive Officer Christoph Westphal, M.D., Ph.D.
Individuals can follow the Company on Twitter (@flexpharma) and the Company's website (http://ir.flex-pharma.com/) to see the latest progress of the Company's pre-launch activities for its consumer product to prevent and treat exercise-associated muscle cramps.
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