LOS ANGELES--(BUSINESS WIRE)--Marketplace’s latest investigative report centers around a single sentence in the original label for Purdue Pharma’s drug OxyContin.
The report is an origin story of the opioid epidemic, told here and in a special episode of Marketplace’s podcast, The Uncertain Hour. The coverage highlights findings from more than eight months of investigative reporting, including the review of hundreds of documents, some of which have been under seal for more than a decade.
The coverage sheds light on the relationship between the Food and Drug Administration, the agency responsible for monitoring and approving prescription drugs, and Purdue Pharma from 1995 to 2001. At the center of the company’s original marketing, aimed at physicians during that time, was a single sentence in OxyContin’s original label:
“Delayed absorption as provided by OxyContin tablets, is believed to reduce the abuse liability of a drug.”
Purdue’s marketing campaign relied on that sentence, which suggested OxyContin was less likely to be abused than other prescription opioids, according to depositions from various sales reps and physicians pitched on the drug. But recently unsealed documents discovered by Marketplace’s reporting on the crisis provide further evidence that the claim was not backed up by clinical studies.
Marketplace’s story highlights new information behind the creation of the crucial sentence that helped set off the opioid crisis, how it wound up in an FDA-approved label, and why it took regulators six years to remove.
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Source: Data are copyright Nielsen Audio and StreamGuys. Data are estimates only.
About The Uncertain Hour:
In The Uncertain Hour® podcast, host Krissy Clark dives into one controversial topic each season to reveal the surprising origin stories of our economy. From the Marketplace Wealth & Poverty Desk, each season goes beyond buzzwords to bust longstanding myths and uncover surprising backstories. On this season of The Uncertain Hour, the team unpacks a ten-letter word that influences our lives every day, from the food we eat to the air we breathe: regulation. Federal regulations affect everything from what’s inside your peanut butter jar, to how the opioid crisis spread, to how we define crime in America. The Uncertain Hour dives deep to uncover what’s behind the origin of regulations in America, the red tape that shapes our democracy, and why it matters now. Because the things we fight the most about are the things we know the least about. Listen and subscribe on your favorite podcast app. Twitter: @UncertainHour