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KEYTRUDA® (pembrolizumab) Plus Padcev® (enfortumab vedotin-ejfv) Significantly Improved Event-Free Survival, Overall Survival and Pathologic Complete Response Rates for Cisplatin-Eligible Patients with MIBC When Given Before and After Surgery

RAHWAY, N.J.--(BUSINESS WIRE)--Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced positive topline results from the Phase 3 KEYNOTE-B15 trial (also known as EV-304) in patients with muscle-invasive bladder cancer (MIBC) who are eligible for cisplatin-based chemotherapy. The trial showed KEYTRUDA® (pembrolizumab) plus Padcev ® (enfortumab vedotin-ejfv), given as neoadjuvant and adjuvant treatment (before and after surgery), demonstrated a statistically signific...
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First Trust Global Funds PLC UK Regulatory Announcement: Net Asset Value(s)

LONDON--(BUSINESS WIRE)--  Funds Date TIDM ISIN Code Shares in Issue Currency Net Asset Value NAV/per Share First Trust Eurozone AlphaDEX UCITS ETF 16.12.2025 FEUD IE00BF2FL590  366,243.00 EUR  18,257,327.51   49.850  ...
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First Trust Global Funds PLC UK Regulatory Announcement: Net Asset Value(s)

LONDON--(BUSINESS WIRE)--  Funds Date TIDM ISIN Code Shares in Issue Currency Net Asset Value NAV/per Share First Trust SMID Rising Dividend Achievers UCITS ETF 16.12.2025 SDVI.LN IE000YVOQ2A3 40,361.00 USD 1,068,875.16 26.483  ...
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HSBC Bank Plc UK Regulatory Announcement: FRN Variable Rate Fix

LONDON--(BUSINESS WIRE)--  15-December-2025 Issue: Clydesdale Bank plc CB Series 10 XS3095269539 Pursuant to our appointment as Agent for the above stated issue, please be advised of the following interest rate determination: Date From: 22-September-2025 Date To: 22-December-2025 Record Date: 19-December-2025 Value Date: 22-December-2025 Benchmark Rate: 3.98849% Margin: 0.8% Total Rate: 4.78849% Floor: 0% Number of Days: 91 Day Count: Actual / 365 (Fixed) Interest Frequency: Quarterly Denominat...
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First Trust Global Funds PLC UK Regulatory Announcement: Net Asset Value(s)

LONDON--(BUSINESS WIRE)--  Funds Date TIDM ISIN Code Shares in Issue Currency Net Asset Value NAV/per Share First Trust Eurozone AlphaDEX UCITS ETF 16.12.2025 FEUZ IE00B8X9NY41 1,103,799.00 EUR  62,017,036.89   56.185  ...
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First Trust Global Funds PLC UK Regulatory Announcement: Net Asset Value(s)

LONDON--(BUSINESS WIRE)--  Funds Date TIDM ISIN Code Shares in Issue Currency Net Asset Value NAV/per Share First Trust SMID Rising Dividend Achievers UCITS ETF 16.12.2025 SDVY.LN IE0001R850E1 10,779,007.00 USD 250,651,682.81 23.254  ...
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HSBC Bank Plc UK Regulatory Announcement: FRN Variable Rate Fix

LONDON--(BUSINESS WIRE)--  15-December-2025 Issue: Clydesdale Bank plc CB SERIES 8 XS2692456200 Pursuant to our appointment as Agent for the above stated issue, please be advised of the following interest rate determination: Date From: 22-September-2025 Date To: 22-December-2025 Record Date: 19-December-2025 Value Date: 22-December-2025 Benchmark Rate: 3.98849% Margin: 0.6% Total Rate: 4.58849% Number of Days: 91 Day Count: Actual / 365 (Fixed) Interest Frequency: Quarterly Denomination: GBP 1,...
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Kallyope To Present at the 44th Annual J.P. Morgan Healthcare Conference

NEW YORK--(BUSINESS WIRE)--Kallyope, a late-stage biotechnology company leveraging unique insights into neural signaling pathways to develop innovative therapies for health challenges faced by hundreds of millions of people globally, today announced that the Company will present at the 44th Annual J.P. Morgan Healthcare Conference to be held January 12-15 in San Francisco, CA. 44th Annual J.P. Morgan Healthcare Conference Presentation Details Presentation Date: Tuesday, January 13, 2025 Present...
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Thompson Street Capital Partners Announces the Launch of Complex Claims Recovery, a Newly Independent Provider of End-to-End Complex Claims Management

ST. LOUIS--(BUSINESS WIRE)--Thompson Street Capital Partners (TCSP), a private equity firm based in St. Louis, announced today the formation of Complex Claims Recovery, a newly independent insurance claims management platform spun out from its health plan subrogation portfolio company Intellivo. The separation establishes two focused platforms positioned for continued growth and innovation within the broader provider and payer markets. Complex Claims Recovery will build upon its strong speciali...
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First Trust Global Funds PLC UK Regulatory Announcement: Net Asset Value(s)

LONDON--(BUSINESS WIRE)--  Funds Date TIDM ISIN Code Shares in Issue Currency Net Asset Value NAV/per Share First Trust Growth Strength UCITS ETF 16.12.2025 FTGS.LN IE000YZLMXT9 25,002.00 USD 551,987.27 22.078  ...