City of Hope Receives $50 Million Gift From Lennar Foundation to Build the Future of Cancer Care

The largest single contribution to City of Hope Orange County will establish Lennar Foundation Cancer Center to accelerate the vision of eradicating cancer and creating healthier communities

Key Takeaways:

  • Lennar Foundation’s transformational gift of hope will advance City of Hope’s plans to develop and operate a nationally recognized comprehensive cancer campus in Irvine, California, and an Orange County network of cancer care.
  • Lennar Foundation Cancer Center at City of Hope Orange County is scheduled to open in 2022, cementing Lennar’s leadership in supporting breakthrough medical treatment, research and discoveries on the East and West coasts.
  • Lennar builds hope and homes, as it helps a community where nearly 20% of patients diagnosed with cancer must travel outside the area for advanced cancer care.
  • The COVID-19 crisis made it clear that cancer doesn’t stop, and Lennar Foundation’s gift reinforces the importance of making highly specialized cancer care, pioneering research and breakthroughs more accessible to patients who need tomorrow’s discoveries today.
  • Together, two nationally recognized organizations disrupt health care delivery and redefine the traditional boundaries of a world-renowned cancer center by extending lifesaving care and research directly into a community, establishing a best practice for the nation.
  • A portion of this gift will support collaborative research between City of Hope and Sylvester Comprehensive Cancer Center, along with the University of Miami and Jackson Memorial health systems on precision medicine approaches to cancer that will help eliminate health inequities.

Lennar Foundation Cancer Center, opening in 2022 (Photo: City of Hope)

IRVINE, Calif.--()--World-renowned cancer research and treatment center City of Hope has received a $50 million gift from Lennar Foundation, the charitable arm of homebuilder Lennar Corporation. This transformational gift of hope is the largest single philanthropic contribution to City of Hope Orange County. It will expedite the health care organization’s bold plans to invest $1 billion to develop and operate a comprehensive cancer campus in Irvine, California, and establish an Orange County network of advanced cancer care and research that will speed groundbreaking treatments directly to a community with growing needs.

The future 190,000-square-foot Lennar Foundation Cancer Center at City of Hope Orange County will be located on 11 acres at Five Point’s Great Park in the heart of Irvine. It will bring best-in-class cancer care, pioneering research and lifesaving treatments to the county’s 3.2 million residents. Construction is already underway on the comprehensive cancer center, which will open in 2022. In addition, Orange County’s only hospital dedicated exclusively to treating and curing cancer will open at City of Hope Irvine in 2025.

City of Hope’s presence in Orange County offers local access to City of Hope’s National Cancer Institute-designated comprehensive cancer center with world-renowned cancer physicians and researchers who are singularly focused on finding better treatments and cures.

Lennar Foundation Cancer Center at City of Hope Orange County will bring to the region a host of distinguishing services, including:

  • Local access to more than 1,000 physicians and researchers who are transforming laboratory breakthroughs into targeted treatments that offer the best hope for patients
  • Access to hundreds of clinical trials that make 21st century treatments available to cancer patients meeting clinical criteria soon after they are developed.
  • A range of treatment options — from chemotherapy to immunotherapy and more — for combatting even the most aggressive cancers
  • New ways for preventing and treating cancer in its early stages, including highly targeted genomics and precision medicine breakthroughs
  • Nationally recognized supportive care programs rooted in more than a century of compassionate caregiving to help patients and their families overcome the psychosocial issues that can accompany a serious illness

As the country emerges from the COVID-19 pandemic, Lennar Foundation’s extraordinary contribution underscores the importance of investing in local health care resources and increasing access to leading-edge care. For Orange County, it is a reminder that cancer does not stop, and that City of Hope’s mission is more important than ever.

Lennar has a long history in Orange County of developing thriving communities, including helping form the vision for a world-class recreation and lifestyle destination. This gift is an extension of this longstanding commitment to improving lives in the regions Lennar helps shape. A portion of the gift to City of Hope is designated to support clinical translational research between City of Hope and the Sylvester Comprehensive Cancer Center of the University of Miami, thus uniting two organizations supported by Lennar’s generosity who share similar goals in developing new treatments and cures for patients with cancer.

City of Hope and Sylvester Comprehensive Cancer Center serve two of the most diverse areas in the United States. Both organizations are committed to conducting high-impact research that addresses the cancer burden in their communities. This gift will enable collaborative, translational science that will drive innovation and catalyze timely and necessary progress towards health equity.

Lennar Foundation’s gift to City of Hope is a generous continuation of Lennar’s longstanding support of the comprehensive cancer center. Jon Jaffe, co-chief executive officer and co-president of Lennar Corporation, is a member of City of Hope’s Construction Industries Alliance Leadership Advisory Council, which raises funds for cancer treatment and research. In recognition of his contributions, Jaffe was awarded City of Hope’s highest honor — The Spirit of Life® Award in 2004.

City of Hope Newport Beach, the first phase of City of Hope Orange County’s expansion, opened in early 2020, providing Orange County residents first-time local access to world-renowned physicians backed by the powerful City of Hope network. City of Hope plans to open other clinical network locations across the region.

Supporting quotes

Robert Stone, president and CEO, City of Hope
Helen and Morgan Chu Chief Executive Officer Distinguished Chair

“This is the start — and it is a monumental start — to show the nation that our work in Orange County will catalyze incredible achievements in health care. Visionary donors and volunteers have been foundational to City of Hope’s 108-year history, and we are deeply grateful to the Lennar Foundation for their extraordinary contributions and longstanding support. With this gift, we will achieve the nexus of unsurpassed medical expertise, future-focused communities, groundbreaking technology and innovation, all for the single purpose of saving lives. This partnership supports a system of care delivery that provides state-of-the-art treatments, the latest scientific and medical discoveries, and unprecedented access that will serve as a model across the country.”

Stuart Miller, executive chairman, Lennar Corporation

“At Lennar, we are committed to building communities, and we are pleased to support City of Hope to help build the future of cancer care. Together, we are building a state-of-the-art center for advanced cancer care and research that will make a difference in the lives of so many by turning science into practice and hope into reality.”

Nicole Petersen Murr, grateful Orange County patient

“City of Hope saved my life. My family and I will be forever grateful to my doctor and care team. Anyone who has heard the words ‘You have cancer’ knows how those words change your life and affect every piece of it. I want everyone who hears those words to have the same compassionate care and access to the latest treatments that I had. Having City of Hope in Orange County changes everything for cancer patients — present and future. I’m so grateful to have this world-renowned care in my own community.”

Annette M. Walker, president, City of Hope Orange County

“This generous gift of hope is a historic moment for City of Hope. Thank you to Lennar Foundation, which is united in our vision and understands the urgency of our work, helping us ensure that our promise to Orange County will be fulfilled. We are building a place of hope and healing that will serve residents of Orange County and beyond for generations to come. Every one of us has been touched by cancer and we want all who are impacted by this disease to know we are here for you, your family, friends and neighbors.”

Jon Jaffe, co-chief executive officer and co-president, Lennar Corporation

“City of Hope is a leader in the treatment of and race to find a cure for cancer, and it’s gratifying to know that, with this gift, we will make a positive impact by expanding access to care and advancing the research that will treat, prevent and ultimately eliminate cancer — we hope this contribution will encourage other philanthropic leaders to support City of Hope in the fight against cancer.”

Kristin J. Bertell, chief philanthropy officer, City of Hope

“This important contribution is a clear demonstration of the power of philanthropy to accelerate positive changes in health care delivery, spur advances in science, research and treatment, and give real hope to patients, families and communities. Lennar Foundation’s generosity continues a long philanthropic legacy that is the cornerstone of our history. There is no doubt that this gift will have a long-lasting impact, and we look forward to engaging the community to make the vision for Orange County and the future of cancer care a reality.”

For more information on the progress of City of Hope’s Orange County expansion and its first clinical network location in Newport Beach, please visit

About City of Hope

City of Hope is an independent biomedical research and treatment center for cancer, diabetes and other life-threatening diseases. Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies, and numerous breakthrough cancer drugs are based on technology developed at the institution. Translational Genomics Research Institute (TGen) became a part of City of Hope in 2016. AccessHope, a wholly owned subsidiary, was launched in 2019, dedicated to serving employers and their health care partners by providing access to City of Hope’s exceptional cancer expertise. A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona. For more information about City of Hope, follow us on Facebook, Twitter, YouTube or Instagram.

About Lennar Corporation

Lennar Corporation, founded in 1954, is one of the nation's leading builders of quality homes for all generations. Lennar builds affordable, move-up and active adult homes primarily under the Lennar brand name. Lennar's Financial Services segment provides mortgage financing, title and closing services primarily for buyers of Lennar's homes and, through LMF Commercial, originates mortgage loans secured primarily by commercial real estate properties throughout the United States. Lennar's Multifamily segment is a nationwide developer of high-quality multifamily rental properties. LENX drives Lennar's technology, innovation and strategic investments. For more information about Lennar, please visit


Nisha Morris, AVP Marketing and Communication
City of Hope Orange County
714-414-3232 or

Danielle Tocco, Vice President Communications
Lennar Corporation
949-789-1633 or

Release Summary

Transformational gift of $50 million from Lennar Foundation is the largest single philanthropic contribution to City of Hope Orange County.


Nisha Morris, AVP Marketing and Communication
City of Hope Orange County
714-414-3232 or

Danielle Tocco, Vice President Communications
Lennar Corporation
949-789-1633 or