TOKYO--(BUSINESS WIRE)--Shinkowa Pharmaceutical Co., Ltd. (Chuo-ward, Tokyo; CEO, Megumi Tanaka)
sells the first ever original supplements and cosmetics containing
β-nicotinamide mononucleotide (NMN) under the "MIRAILAB" supplement
brand and the "MIRAIDA" cosmetic brand, respectively.
The
company has begun world-wide distribution of the special supplement
products "NMN PURE 3000" and "NMN PURE 1500", which contain high doses
of NMN.
[About NMN]
NMN is an abbreviation of β-nicotinamide
mononucleotide, which is contained in vitamin B3s and exists naturally
in the tissues and cells of organisms.
NMN is transformed in the body to a substance called nicotinamide adenine dinucleotide (NAD), which is necessary for us to maintain body functions, and is known to enhance the activities of 7 types of sirtuin genes (SIRT 1-7) as well as the function of mitochondria within the cells.
Mitochondria produce adenosine triphosphate (ATP), known as the "molecular unit of currency", and play a role in providing energy to the cells. SIRT 1 is important in promoting the cooperation of the nucleus and mitochondria within the cells.
As mitochondria function decreases with aging, the production of NMN in
the body decreases, and the amount of NAD decreases accordingly.
When
taken orally, about 90% of the NAD is destroyed in the digestive organs,
therefore NMN, which is not destroyed in the digestive organs, needs to
be supplemented from outside the body. NMN intake enhances the function
of mitochondria, and rejuvenation and anti-aging are anticipated with
the activation of sirtuin genes.
Sirtuin genes play an important role in controlling aging and longevity.
Proteins produced from sirtuin genes prevent aging and are involved in
energy metabolism.
For example, the functions of the muscles, etc.
are known to be kept young when the function of SIRT1 is enhanced by NMN
in the hypothalamus of the brain. The hypothalamus is considered to play
the role of the "control center" that regulates aging. Commands from the
hypothalamus are conveyed to the skeletal muscles, and a hormone-like
substance that adjusts the body function is excreted from the skeletal
muscles to keep the muscles young. Therefore, NMN is expected to be
effective not only for decreasing body functions associated with aging
but also for locomotive syndrome, which makes walking difficult due to
the weakening of the legs, and sarcopenia, which is associated with a
decrease in muscle mass.
NMN is also expected to be effective for various functions that are weakened with aging and diseases, including the improvements in the blood glucose level in patients with type 2 diabetes and pre-diabetes in whom the blood glucose levels become higher than normal, prevention of Alzheimer's disease, neurodegenerative disease, heart failure, and metabolic syndrome, as well as increased bone mineral density and the improved immunity. These conditions have already been confirmed to be resolved and improved after treatment with NMN in studies with mice.
[Product Overview] | ||
(1) NMN PURE 3000 | ||
Price: US$1098 | ||
Size: 60 capsules (50 mg of NMN/capsule, 3,000 mg of NMN/bottle) | ||
Serving: 1-2 capsules/day | ||
Ingredients: starch, nicotinamide mononucleotide | ||
Supplement facts: (serving size: 2 capsules): | Calories 1.89 kcal/Protein 0.03 g/Fat 0.00 g/Carbohydrate 0.43 g/Sodium 0.36 mg/Salt 0.001 g | |
(2) NMN PURE 1500 | ||
Price: US$607 | ||
Size: 60 capsules (25 mg of NMN/capsule, 1,500 mg of NMN/bottle) | ||
Serving: 2-4 capsules/day | ||
Ingredients: Starch, nicotinamide mononucleotide | ||
Supplement facts: (serving size: 4 capsules): | Calories 4.76 kcal /Protein 0.04 g/Fat 0.00 g/Carbohydrate 1.13 g/Sodium 0.76 mg/Salt 0.001 g | |
[Purchase]
Available online at the following address:
[Precautions]
The NMN contained in the NMN-containing supplements
and cosmetics distributed by Shinkowa Pharmaceutical Co., Ltd. is 98% or
more in purity, and its safety has been confirmed by acute toxicity
test, primary skin irritation test, eye irritation test and reverse
mutation test.
This product information is intended for customers to use as a reference when selecting products and is not a substitute for the opinions of physicians, pharmacists and other qualified specialists. It cannot be used for self-diagnosis to cure diseases. Please consult with your doctor before purchase if you have allergies or are pregnant.
After you receive the product, please avoid subjecting it to direct sunlight, high temperature and humidity and store it in a dark, cool place such as in a refrigerator even before opening.
[Company Profile]
Company name: Shinkowa Pharmaceutical Co.,Ltd.
Representative:
Megumi Tanaka, CEO
Address: 2-30-11 Shinkawa, Chuo-Ward, Tokyo
104-0033 Japan
Business description: Health food/cosmetics
distribution, trade business
URL: http://shinkowapharma.com/