Research Conducted with Mayo Clinic Practitioners and Kalish Institute Confirms Efficacy of Functional Medicine

Positive Results Found from First-Ever Pilot Study using an Integrative Approach to Fatigue, Stress and Digestive Disorders

OAKLAND, Calif.--()--A research team, including Daniel J. Kalish, founder of the Kalish Institute and Susanne M. Cutshall and Larry R. Bergstrom, currently practicing at Mayo Clinic, proudly release a study around functional medicine. The study shows a variety of stress, fatigue and quality of life measures can be improved through functional medicine, a growing field utilizing lab-based supplement programs, including lifestyle and nutritional counseling.

The 28-week study assessed the effectiveness of a specific functional medicine approach for improving stress, energy, fatigue, digestive issues and quality of life in middle-aged women exposed to high-stress work environments. This method, known as the Kalish Method and taught exclusively through the Kalish Institute, provides a systems approach to chronic illness addressing the “whole person” rather than an isolated set of symptoms, and restoring three key body systems: hormones, digestion and detoxification.

“The Kalish Institute has been offering training in functional medicine for over 10 years and we’re pleased this study confirmed our approach is effective in treating key health issues that affect so many people on a daily basis, including stress and fatigue” said Dr. Kalish, Founder of the Kalish Institute. “As the first research study to test this type of holistic approach, we’re hopeful these positive results will open doors for future studies of this kind and continue to boost the adoption of functional medicine practices.”

In this study, 21 women ages 30 to 55, received a functional medicine treatment consisting of lifestyle interventions, protocols to treat HPA-axis dysfunction and various gut infections. The analysis showed:

  • A 38 percent average decrease in fatigue, which was measured through a Profiles of Mood States (POMS) questionnaire
  • A 27 percent average decrease in stress, calculated through the Visual Analog Scale (VAS)
  • An increase in vitality by an average of 39 percent, calculated through the SF-36 quality of life questionnaire
  • A 22 percent average decrease in confusion, measured through a POMS questionnaire
  • Reduction in H. pylori infections, which can be associated with chronic inflammation and digestive symptoms

The study, which was completed in April 2015, has been published in the May 2016 issue of Complementary Therapies in Clinical Practice.

For practitioners interested in adopting functional medicine practices, the Kalish Institute offers a robust but easy-to-learn program that has trained over 1,000 practitioners worldwide, including staff of the Mayo and Cleveland clinics, as well as Dr. Mercola’s Optimum Health Clinic. The training helps physicians effectively restore the physical and emotional health of their patients.

For all press/media inquiries, please contact Alafair Hall at Stanton & Company at

About The Kalish Institute:

The Kalish Institute, founded in 2006 by Daniel Kalish, D.C., is the leading online functional medicine training program, delivering a true mentorship experience integrating clinical training and practice management on a state-of-the-art educational platform. Kalish Institute graduates constitute a thriving interdisciplinary community focused on collaborative and case-based learning models for building successful functional medicine practices.


Stanton & Company
Alafair Hall, 310-305-7800

Release Summary

Research conducted with Mayo Clinic practitioners confirms efficacy of functional medicine in first-ever pilot study


Stanton & Company
Alafair Hall, 310-305-7800