ALKS 8700 Drug Analysis 2018: An Oral Monomethyl Fumarate Molecule Being Developed for the Treatment of Relapsing Multiple Sclerosis - ResearchAndMarkets.com

DUBLIN--()--The "Drug Analysis: ALKS 8700" drug pipelines has been added to ResearchAndMarkets.com's offering.

ALKS 8700 is an oral monomethyl fumarate molecule being developed for the treatment of relapsing multiple sclerosis.

Alkermes designed this drug to have Tecfidera-like efficacy, but to also display superior gastrointestinal tolerability. After being administered, ALKS 8700 rapidly metabolizes into monomethyl fumarate.

While the actual mechanism of monomethyl fumarate is unknown, the molecule has been shown to activate the nuclear factor (erythroid-derived 2)-like 2 pathway, which is involved in the cellular response to oxidative stress.

ALKS 8700 is currently in the middle of its pivotal Phase III clinical trial program, with Alkermes planning to submit a 505(b)(2) New Drug Application in 2018.

Key Topics Covered:

List of Figures
Figure 1: ALKS 8700 for multiple sclerosis - SWOT analysis
Figure 2: Drug assessment summary of ALKS 8700 for multiple sclerosis
Figure 3: Drug assessment summary of ALKS 8700 for multiple sclerosis
Figure 4: ALKS 8700 sales for multiple sclerosis across the US and five major EU markets, by country, 2016-25

List of Tables
Table 1: ALKS 8700 drug profile
Table 2: ALKS 8700 Phase III trials in multiple sclerosis
Table 3: ALKS 8700 sales for multiple sclerosis across the US and five major EU markets, by country ($m), 2016-25

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Related Topics: Central Nervous System Drugs

Contacts

ResearchAndMarkets.com
Laura Wood, Senior Manager
press@researchandmarkets.com
For E.S.T Office Hours Call 1-917-300-0470
For U.S./CAN Toll Free Call 1-800-526-8630
For GMT Office Hours Call +353-1-416-8900
Related Topics: Central Nervous System Drugs