DUBLIN--(BUSINESS WIRE)--The "Acyl
CoA Desaturase (Fatty Acid Desaturase or Delta 9 Desaturase or Stearoyl
CoA Desaturase or SCD or EC 1.14.19.1) - Pipeline Review, H2 2017"
report has been added to Research and Markets' offering.
The
report 'Acyl CoA Desaturase - Pipeline Review, H2 2017' outlays
comprehensive information on the Acyl CoA Desaturase (Fatty Acid
Desaturase or Delta 9 Desaturase or Stearoyl CoA Desaturase or SCD or EC
1.14.19.1) targeted therapeutics, complete with analysis by indications,
stage of development, mechanism of action (MoA), route of administration
(RoA) and molecule type; that are being developed by Companies /
Universities.
'Acyl CoA Desaturase - Pipeline Review, H2
2017'; Acyl CoA Desaturase (Fatty Acid Desaturase or Delta 9 Desaturase
or Stearoyl CoA Desaturase or SCD or EC 1.14.19.1) pipeline Target
constitutes close to 7 molecules. Out of which approximately 7 molecules
are developed by Companies.
Acyl CoA Desaturase Stearoyl-CoA
desaturase 1 is a protein encoded by the SCD gene. Stearoyl-CoA
desaturase-1 plays an important enzyme in fatty acid metabolism.
Alteration in SCD1 expression changes the fatty acid profile of these
lipids and produces diverse effects on cellular function.
High
SCD1 expression is correlated with metabolic diseases such as obesity
and insulin resistance, whereas low levels are protective against these
metabolic disturbances. SCD1 is also involved in the regulation of
inflammation and stress in distinct cell types, including -cells,
adipocytes, macrophages, endothelial cells, and myocytes. Complete loss
of SCD1 expression has been implicated in liver dysfunction and several
inflammatory diseases such as dermatitis, atherosclerosis, and
intestinal colitis.
Key Topics Covered:
- Introduction
- Overview
- Therapeutics Development
- Products under Development by Stage of Development
- Products under Development by Therapy Area
- Products under Development by Indication
- Products under Development by Companies
- Therapeutics Assessment
- Assessment by Mechanism of Action
- Assessment by Route of Administration
- Assessment by Molecule Type
- Companies Involved in Therapeutics Development
- Daiichi Sankyo Co Ltd
- Galmed Pharmaceuticals Ltd
- Johnson & Johnson
- Novartis AG
- Takeda Pharmaceutical Co Ltd
- Thesan Pharmaceuticals Inc
For more information about this report visit https://www.researchandmarkets.com/research/8ff7pj/acyl_coa