DUBLIN--(BUSINESS WIRE)--Research and Markets (http://www.researchandmarkets.com/research/8kscm2/protein_kinase) has announced the addition of the "Protein Kinase Inhibitors in Oncology Drug Pipeline Update" report to their offering.
Protein kinase inhibitors such as Gleevec, Iressa and Tarceva have allowed the biotechnology industry to deliver on the promise of targeted cancer drugs. However, these three successful drugs are just the top of an emerging line of therapy. Given the fact that they all target tyrosine kinases and that kinase mutations can cause patients to become resistant to these drugs, there is plenty of room for more competition.
There are today 448 companies plus partners developing 790 PKI drugs in 2754 developmental projects in cancer. In addition, there are 4 suspended drugs and the accumulated number of ceased drugs over the last years amount to another 448 drugs. Protein Kinase Inhibitors In Oncology Drug Pipeline Update lists all drugs and gives you a progress analysis on each one of them. Identified drugs are linked to 291 different targets.
All included targets have been cross-referenced for the presence of mutations associated with human cancer. To date 287 out of the 288 studied drug targets so far have been recorded with somatic mutations. The software application lets you narrow in on these mutations and links out to the mutational analysis for each of the drug targets for detailed information. All drugs targets are further categorized on in the software application by 51 classifications of molecular function and with pathway referrals to BioCarta, KEGG, NCI-Nature and NetPath.
Drug Pipeline Update at a Glance
Investigators
Includes more than 448 principal companies plus their collaborators. There is direct access from inside the application to web pages of all principal companies.
Note: You are able to sort and find drugs according to companies and partners from drop-down menus in the application. You may also sort and find drugs according to country of companies.
Drug name & Synonyms
Lists commercial, generic and code names for drugs.
Developmental stage
This Drug Pipeline Update contains 790 PKI drugs in development, which have a total of 2754 developmental projects in cancer. In addition there are suspended and ceased drugs.
Pipeline Breakdown According to Number of Drugs
Marketed - 40
Registered - 1
Pre-registration - 9
Phase III - 68
Phase II - 224
Phase I - 289
Preclinical - 419
No Data - 21
Suspended - 4
Ceased - 448
For more information visit http://www.researchandmarkets.com/research/8kscm2/protein_kinase
