DUBLIN--(BUSINESS WIRE)--Research and Markets (http://www.researchandmarkets.com/research/wvjpwz/competitor) has announced the addition of the "Competitor Analysis: Inhibitors of the Bromodomain and Extra-Terminal Domain (BET) Family" report to their offering.
The Competitive Intelligence Report Inhibitors of the bromodomain and extra-terminal domain (BET) family as of January 2016 provides a competitor analysis in the development pipeline of novel small molecule pan, selective or dual target bromodomain and extra-terminal domain (BET) family inhibitors suitable for treatment of cancer, inflammatory and cardiovascular diseases.
Bromodomains are epigenetic readers of histone acetylation involved in chromatin remodeling and transcriptional regulation. Bromodomains have attracted great interest as promising new epigenetic targets for diverse human diseases, including inflammation, cancer, and cardiovascular disease.
The demonstration that two small molecule compounds, JQ1 and I-BET762, potently inhibit proteins of the bromodomain and extra-terminal (BET) family with potential for cancer and inflammatory disease sparked intense efforts in academia and pharmaceutical industry to develop novel bromodomain antagonists for therapeutic applications. Several BET inhibitors are already in clinical trials for hematological malignancies, solid tumors and cardiovascular disease.
The report includes a compilation of currently active projects in research and development of novel small molecules targeting for treatment of hematologic malignancies, solid tumors, inflammatory and cardiovascular diseases. In addition, the report lists company-specific R&D pipelines of BET Inhibitors.
Competitor projects are listed in a tabular format providing Information on:
- Drug Codes
- Target/Mechanism of Action
- Class of Compound
- Company
- Product category/Therapeutic Area
- Indication
- R&D Stage
Key Topics Covered:
1. Inhibitors of the bromodomain and extra-terminal domain (BET) family
2. Corporate BET Inhibitor R&D Pipelines
For more information visit http://www.researchandmarkets.com/research/wvjpwz/competitor
