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ルベド・ライフ・サイエンシズ、GPX4モジュレーター「RLS-1496」を用いた脱毛症治療の臨床試験を発表し、初のヒトex vivoエビデンスにより毛包の顕著な成長を実証

カリフォルニア州マウンテンビュー--(BUSINESS WIRE)--(ビジネスワイヤ) -- ルベド・ライフ・サイエンシズ(Rubedo Life Sciences, Inc.、以下「ルベド」)は、男性型脱毛症(AGA)患者を対象とする開発中のRLS-1496の新たな臨床試験を2026年10月に開始し、初期データは2027年上半期に得られる見込みであると発表しました。本試験は、脱毛症を対象とするGPX4モジュレーターの初の臨床評価となり、RLS-1496が、種類を問わずヒト臨床試験に進んだ世界初のGPX4モジュレーターであることを確立した開発プログラムをさらに発展させるものです。 RLS-1496は、日光角化症および皮膚老化のほか、乾癬やアトピー性皮膚炎などの皮膚疾患を対象とする臨床試験ですでに有効性を示しており、ヒトにおける新たなエビデンスにより、病的老化細胞を除去するとともに、ストレスを受けた老化細胞(幹細胞や前駆細胞を含む)のNRF2経路を調節することでレドックス・リセットを促進する二重のSenoAdaptive作用機序が示されています。ヒト毛包を用いたAGAモデルのex v...
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First Trust Global Funds PLC UK Regulatory Announcement: Net Asset Value(s)

LONDON--(BUSINESS WIRE)--  Funds Date TIDM ISIN Code Shares in Issue Currency Net Asset Value NAV/per Share First Trust Vest U.S. Equity Buffer UCITS ETF - July 16.09.2026 FJUL.LN IE000YJBT6I5  100,002.00 USD   2,905,090.59   29.050  ...
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AMRA Medical Earns TIME’s Highest “Outstanding” Rating in World’s Top HealthTech Companies 2026

LINKÖPING, Sweden--(BUSINESS WIRE)--AMRA Medical Earns TIME’s Highest “Outstanding” Rating in World’s Top HealthTech Companies 2026...
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Qube Research & Technologies LTD UK Regulatory Announcement: Form 8.3

LONDON--(BUSINESS WIRE)--  Ap27 FORM 8.3 IRISH TAKEOVER PANEL OPENING POSITION DISCLOSURE/DEALING DISCLOSURE UNDER RULE 8.3 OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVER RULES, 2022 BY PERSONS WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE 1. KEY INFORMATION (a) Full name of discloser Qube Research & Technologies Limited (b) Owner or controller of interests and short positions disclosed, if different from 1(a) The naming of nominee or vehicle companies is insufficient. For...
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First Trust Global Funds PLC UK Regulatory Announcement: Net Asset Value(s)

LONDON--(BUSINESS WIRE)--  Funds Date TIDM ISIN Code Shares in Issue Currency Net Asset Value NAV/per Share First Trust Vest U.S. Equity Buffer UCITS ETF 10% - January 16.09.2026 FJAN.LN IE000MDKBOB3  150,002.00 USD   4,397,748.67   29.318  ...
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NATIXIS UK Regulatory Announcement: Form 8.3 Schroders plc

LONDON--(BUSINESS WIRE)--  FORM 8.3 PUBLIC OPENING POSITION DISCLOSURE/DEALING DISCLOSURE BY A PERSON WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE Rule 8.3 of the Takeover Code (the “Code”) 1. KEY INFORMATION (a) Full name of discloser: NATIXIS SA (b) Owner or controller of interests and short positions disclosed, if different from 1(a): The naming of nominee or vehicle companies is insufficient. For a trust, the trustee(s), settlor and beneficiaries must be named.   (c) Name o...
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First Trust Global Funds PLC UK Regulatory Announcement: Net Asset Value(s)

LONDON--(BUSINESS WIRE)--  Funds Date TIDM ISIN Code Shares in Issue Currency Net Asset Value NAV/per Share First Trust Vest U.S. Equity Buffer UCITS ETF - April 16.09.2026 FAPR.LN IE000WX2HZQ7  200,002.00 USD   5,204,460.98   26.022  ...
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H5 Resources Named an OpenAI Select Partner

KAMPALA, Uganda--(BUSINESS WIRE)--H5 Resources, a Uganda-based tin producer rebuilding the historic Mwerasandu mine with applied AI, has been named an OpenAI Select Partner....
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NATIXIS UK Regulatory Announcement: Form 8.3 Rotork plc

LONDON--(BUSINESS WIRE)--  FORM 8.3 PUBLIC OPENING POSITION DISCLOSURE/DEALING DISCLOSURE BY A PERSON WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE Rule 8.3 of the Takeover Code (the “Code”) 1. KEY INFORMATION (a) Full name of discloser: NATIXIS SA (b) Owner or controller of interests and short positions disclosed, if different from 1(a): The naming of nominee or vehicle companies is insufficient. For a trust, the trustee(s), settlor and beneficiaries must be named.   (c) Name o...
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TIAA-CREF UK Regulatory Announcement: Form 8.3

LONDON--(BUSINESS WIRE)--  FORM 8.3 PUBLIC OPENING POSITION DISCLOSURE/DEALING DISCLOSURE BY A PERSON WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE Rule 8.3 of the Takeover Code (the “Code”) 1. KEY INFORMATION (a) Full name of discloser: Teachers Insurance and Annuity Association of America/TIAA-CREF Investment Management, LLC/ Nuveen Asset Management, LLC (b) Owner or controller of interests and short positions disclosed, if different from 1(a): The naming of nominee or vehicle...