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アジーナス、「ESMO GI 2026」で活動性肝転移を伴わない難治性MSS転移性大腸がんにおける3年時点の全生存率33%を示す画期的なBOT+BALデータを発表
マサチューセッツ州レキシントン--(BUSINESS WIRE)--(ビジネスワイヤ) -- 免疫腫瘍学のイノベーションをリードするアジーナス(Agenus Inc.)(Nasdaq:AGEN)は、活動性肝転移を伴わない難治性マイクロサテライト安定性(MSS)転移性大腸がん(mCRC)患者を対象に、Fc強化型の多機能抗CTLA-4抗体であるボテンシリマブ(BOT)と抗PD-1抗体であるバルスチリマブ(BAL)の併用を評価する、患者登録が完了した第1b相C-800-01コホートから得られた3年ランドマークデータを発表しました。本データは、ドイツ・ミュンヘンで開催された欧州臨床腫瘍消化器癌会議2026(European Society for Medical Oncology Gastrointestinal Cancers(ESMO GI)Congress 2026)で、7月2日に発表されました。 BOT+BALは、従来の免疫チェックポイント阻害薬によるベネフィットがこれまで限定的であり、標準療法で病勢進行した後には持続的な効果をもたらす治療選択肢が少ない、前治療歴の多い患者集団におい...
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Riassunto: Agenus condivide ad ESMO GI 2026 dati storici dello studio BOT+BAL che evidenziano una sopravvivenza globale a tre anni del 33% al carcinoma colorettale metastatico MSS refrattario senza metastasi epatiche attive
LEXINGTON, Massachusetts--(BUSINESS WIRE)--Agenus Inc. (Nasdaq: AGEN), leader nell’innovazione in campo immuno-oncologico, ha annunciato oggi i dati di riferimento relativi alla fase 1b, raccolti nell’arco di tre anni, provenienti dalla coorte completa C-800-01, che valuta il botensilimab (BOT), un anticorpo anti-CTLA-4 multifunzionale potenziato con Fc, in combinazione con balstilimab (BAL), un anticorpo anti-PD-1, in pazienti affetti da carcinoma colorettale metastatico (mCRC) refrattario, co...
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SePRO Corporation Becomes SEPRO Scientific™, Reflecting Science-Led Leadership and Environmental Stewardship
CARMEL, Ind.--(BUSINESS WIRE)--SEPRO Scientific™, formerly known as SePRO Corporation, today announced the launch of a comprehensive brand refresh that unifies the company’s Water and Land divisions under the SEPRO Scientific name. The evolution reflects the company’s continued focus on delivering customer value through science-led insights, digitally-integrated solutions, and measurable outcomes, while reinforcing its long-standing commitment to science as the foundation for solving complex en...
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Agenus présente à l’ESMO GI 2026 des données marquantes sur le traitement BOT+BAL, montrant un taux de survie globale à trois ans de 33 % chez les patients atteints d’un cancer colorectal métastatique réfractaire de type MSS sans métastases...
LEXINGTON, Massachusetts--(BUSINESS WIRE)-- Agenus présente à l’ESMO GI 2026 des données marquantes sur le traitement BOT+BAL, montrant un taux de survie globale à trois ans de 33 % chez les patients atteints d’un cancer colorectal métastatique réfractaire de type MSS sans métastases hépatiques actives Agenus Inc. (Nasdaq : AGEN), leader de l’innovation en immuno-oncologie, a annoncé aujourd’hui les données marquantes à trois ans de l’étude de phase 1b menées sur la cohorte C-800-01, dont le r...
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Agenus präsentiert auf der ESMO GI 2026 bahnbrechende BOT+BAL-Daten, die ein dreijähriges Gesamtüberleben von 33 % bei refraktärem MSS-metastasiertem Kolorektalkarzinom ohne aktive Lebermetastasen belegen
LEXINGTON, Massachusetts--(BUSINESS WIRE)--Agenus Inc. (Nasdaq: AGEN), ein Marktführer im Bereich der immunonkologischen Innovation, präsentierte heute wegweisende Daten aus der dreijährigen Phase-1b-Studie zur vollständig rekrutierten C-800-01-Kohorte, in der Botensilimab (BOT), ein Fc-verstärkter multifunktionalen Anti-CTLA-4-Antikörper, in Kombination mit Balstilimab (BAL), ein Anti-PD-1-Antikörper, bei Patienten mit refraktärem mikrosatellitenstabilem (MSS) metastasiertem Kolorektalkarzinom...
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Agenus presenta en ESMO GI 2026 resultados clave de BOT+BAL: supervivencia global a tres años del 33 % en cáncer colorrectal metastásico MSS refractario sin metástasis hepáticas activas
LEXINGTON, Massachusetts--(BUSINESS WIRE)--Agenus Inc. (Nasdaq: AGEN), empresa líder en innovación en inmunooncología, anunció hoy los resultados a tres años de fase 1b de la cohorte completa C-800-01, que evalúa botensilimab (BOT), un anticuerpo anti-CTLA-4 multifuncional potenciado con Fc, en combinación con balstilimab (BAL), un anticuerpo anti-PD-1, en pacientes con cáncer colorrectal metastásico (mCRC) estable a nivel de microsatélites (MSS) y refractario, sin metástasis hepáticas activas....
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Conti Federal Awarded $43.9 Million Ellsworth Air Force Base Environmental Protection Shelter Project
RAPID CITY, S.D.--(BUSINESS WIRE)--Conti Federal Services LLC, a leading federal construction and design-build firm, has been awarded a $43.9M firm-fixed-price contract for the B-21 60 Row South Environmental Protection Shelters (EPS) at Ellsworth Air Force Base (AFB), South Dakota. Awarded by the U.S. Army Corps of Engineers (USACE) Omaha District, the shelters provide protection for the B-21 Raider, extending the life of the aircraft. Conti Federal’s scope of work includes the construction of...
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KBRA Releases Research – A Quieter Forecast, but No Clear Skies for Insurers
NEW YORK--(BUSINESS WIRE)--KBRA releases research previewing the 2026 Atlantic hurricane season (June 1 to November 30). While the season is forecast to be below normal, it does not eliminate catastrophe risk. Even a quiet season can produce a single storm that generates outsized insured losses if it strikes a high-value, coastal market. Insurers enter this season with stronger capital, improved underwriting results, and broader reinsurance availability than in 2022-23. At the same time, rate p...
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Herbal Essences Launches "Scent of Your Dreams," a Campaign Featuring Amaya Papaya Emphasizing Fragrance for Mood and Well-being
CINCINNATI--(BUSINESS WIRE)--Herbal Essences has always known something the beauty industry is only now catching up to: fragrance is a powerful emotional tool for self-care and mood transformation. People don't just use Herbal Essences products — they love the way those products smell. The brand's new campaign, "Scent of Your Dreams," is built entirely on that truth. Now live across Herbal Essences' social media channels, "Scent of Your Dreams" reframes fragrance as a dopamine-driven, mood-tran...
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Origami Risk Launches New Platform Innovations That Embed AI and Extend Operational Workflows
CHICAGO--(BUSINESS WIRE)--Origami Risk, the industry-leading risk, safety and insurance Software as a Service (SaaS) technology firm, today announced new and enhanced platform capabilities as part of its Q2 2026 Release. Origami Risk's next-generation Admin Portal is at the forefront of the company's latest innovations, providing clients with a powerful standalone administrative console that simplifies platform management through intuitive self-service capabilities. The release also introduces...