Research and Markets: Inflammation and Allergy Drug Design - Cytokines, Chemokines, Grow Factors and Mediators

DUBLIN--(BUSINESS WIRE)--Research and Markets (http://www.researchandmarkets.com/research/e497a0/inflammation_and_a) has announced the addition of John Wiley and Sons Ltd's new book "Inflammation and Allergy Drug Design" to their extensive offering of pharmaceutical science publications.

Our knowledge and understanding of allergic diseases of the respiratory tract has improved to a point where new therapies are being developed for patient benefit.

Inflammation and Allergy Drug Design explains the biologic science that underpins the pathophysiology of asthma and related disorders, as well as their mechanisms. This authoritative guide consists of 25 chapters, each detailing the cutting-edge developments in a particular field. It is divided into three parts, covering cytokines, chemokines, grow factors and mediators.

This book allows immunologists, allergologists and researchers in the pharmaceutical industry to learn and appreciate the target biology in drug development. It also provides medical and pharmaceutical postgraduate students and clinicians with a basic understanding of allergic diseases in the respiratory tract.

Key Topics Covered:

• Novel anti-infl ammatory drugs based on targeting lung dendritic cells and airway epithelial cells
• Role of Th2 cells in the allergic diathesis
• Importance of Th17- and Th1-associated responses for the development of asthma
• Regulatory T cells
• A role for natural killer T-cell subsets in the pathogenesis of various allergic disorders
• Regulatory roles of B cells in allergy and inflammation
• Mast cells
• Eosinophils
• Basophils in infl ammation and allergy drug design
• Epithelial cells
• Fibroblasts
• Airway smooth muscle cells
• Interleukin 4, interleukin 13, and interleukin 9
• Interleukin 3, interleukin 5, and granulocyte-macrophage colony-stimulating factor
• Interleukin 15, interleukin 17, and interleukin 25
• Thymic stromal lymphopoietin
• Interleukin 10
• Tumor necrosis factor alpha
• Profi brotic and angiogenic factors in asthma
• Chemokines
• Epithelial growth factors
• Prostanoids
• Leukotrienes
• Proteases in allergy
• Toll-like receptors

For more information visit http://www.researchandmarkets.com/research/e497a0/inflammation_and_a