Aperio Implements BigTIFF, Donates Enhancements to Public Domain

Digital Pathology Leader Extends Support for TIFF Standard to Image Files Larger than 4GB, Creates Worlds First Terapixel Image

VISTA, Calif.--()--Aperio Technologies, Inc., the leading provider of digital pathology systems and services for the healthcare and life sciences industry, is pleased to announce it has implemented support for BigTIFF - Tagged Image File Format for files which are larger than 4 gigabytes - across all its products and systems. This enhancement to the TIFF standard enables image files larger than 4GB to be created and processed, in a backward-compatible fashion. As part of its commitment to open standards, Aperio has donated these enhancements to the public domain, and is working with the TIFF standards body to incorporate them into a future standard release.

This enhancement makes it possible to create very large high resolution digitized images of bone marrow and peripheral blood smears as part of my work with Aperios new high power oil immersion ScanScopes, stated Douglas Tkachuk, MD and Associate Professor at the University of Toronto.

Aperio's ScanScope® slide scanning systems create digital images of entire microscope slides at gigapixel resolution in minutes. These digital slide images are very large, with dimensions that routinely exceed 100,000 x 100,000 pixels. The TIFF standard is perfect for storing digital slides - it is an open standard supported by a large number of applications on a wide variety of platforms. Until recently TIFF files were limited in size to 4GB, or about 30 gigapixels. With BigTIFF support it is now possible to store images of all sizes, including those larger than 4GB, in the TIFF format. The BigTIFF design was first proposed in 2004 by Joris Van Damme of Aware Systems, and has been refined in online discussions on the TIFF message boards.

Aperio believes strongly in open standards and anticipates that with this enhancement, TIFF will continue to be the standard for storing and managing very large images such as digital slides, stated Ole Eichhorn, chief technology officer for Aperio.

The libtiff library is an open-source cross-platform library which enables applications software to read and write images stored as TIFF files. A new version of libtiff has been created by Aperio which supports BigTIFF files. The new version is backward-compatible with previous versions and in many cases applications software will not have to change in order to create and process BigTIFF files. Aperio has posted detailed information at http://bigtiff.org/ including an overview of the changes, sample BigTIFF images, source code and library downloads, and technical details for the changes which have been made.

As a demonstration of the new capabilities of libtiff, Aperio has created the worlds first terapixel image. (1 terapixel = 1 trillion pixels.) This image is over one million pixels wide, and consists of 225 copies of a breast cancer digital slide combined together. This amazing terapixel image was compressed into a TIFF file size of 143GB. The image may be viewed in any standard web browser using Aperios image viewing technology at: http://bigtiff.org/terapixel.htm.

About Aperio Technologies, Inc.

Aperio provides systems and services for digital pathology. Our award-winning ScanScope® slide scanning systems and SpectrumTM digital pathology information management software is helping pathology professionals around the world improve the efficiency and quality of pathology services, enhance patient care, and improve the bottom line. Applications include remote viewing, archival and retrieval, digital conferencing, research and education, and image analysis. For more information and to view a gallery of digital slides created by ScanScope Systems, visit www.aperio.com.

Contacts

Aperio
Kevin Whiteley, 760-539-1177
Vice President, Marketing
kwhiteley@aperio.com
or
Myla Wagner Public Relations
Myla Wagner, 925-736-7515
myla@mylawagnerpr.com

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Contacts

Aperio
Kevin Whiteley, 760-539-1177
Vice President, Marketing
kwhiteley@aperio.com
or
Myla Wagner Public Relations
Myla Wagner, 925-736-7515
myla@mylawagnerpr.com