Twelve and LanzaTech Partner to Create Ethanol From CO2

Collaborative process seeks to eliminate the fossil fuel impact of ethanol production

Ethanol made from air (Photo: Business Wire)

BERKELEY, Calif.--()--Carbon transformation company Twelve and biotechnology company LanzaTech have transformed CO2 emissions into ethanol as a part of an ongoing research and development partnership.

The two companies combined technology capabilities to create ethanol, which is a common alcohol used as fuel, and an ingredient in hand sanitizers, personal care, and household cleaning products. Ethanol is typically produced using biological processes or as a petrochemical, through ethylene hydration, using fossil fuels. It's also often produced using corn and other crop feedstocks, but this approach is dependent on crops that otherwise could be used to grow food or waste feedstocks. Twelve and LanzaTech are eliminating fossil fuels from ethanol production by converting CO2 to CO through Twelve’s carbon transformation technology, and subsequently using LanzaTech’s small Continuous Stirred Tank Reactor (CSTR) to convert CO to ethanol. This approach is highly scalable and could ultimately produce ethanol at an industrial scale, while simultaneously eliminating CO2 emissions.

“Collaboration is critical to our work in a rapidly evolving technology space. As we use carbon transformation to address long-standing climate challenges, developing pathways to ethanol and other critical products are key to a fossil free future,” said Twelve Co-Founder and CSO Etosha Cave.

“Our partnership with Twelve provides us with the feedstock needed to create critical resources like ethanol without adding CO2 to the atmosphere. Our process aims to rebalance the overabundance of carbon in our environment and instead reuse it for meaningful applications,” said LanzaTech CEO Dr. Jennifer Holmgren.

In Fall 2021, Twelve and LanzaTech also announced plans to develop polypropylene from CO2 with a grant from Impact Squared. This work will see Twelve converting CO2 to CO, which will in turn be converted by LanzaTech’s proprietary microbe to isopropyl alcohol (IPA). Finally, TotalEnergies, based on its alcohols dehydration knowhow (AtolTM), will dehydrate it into propylene which will be polymerized into polypropylene with the same technical characteristics as its fossil counterparts. Polypropylene is a major polymer used in key applications, including medical devices like syringes and IV bags, automotive, furniture, textiles, and other durable products.

About Twelve

Twelve is the carbon transformation company, a new kind of chemical company built for the climate era. We make essential products from air, not oil. Our groundbreaking technology eliminates emissions by transforming CO2 into critical chemicals, materials and fuels that today are made from fossil fuels. We call it carbon transformation, and it fundamentally changes how we can address climate change, reduce emissions and reverse the carbon imbalance. Reinventing what it means to be a chemical company, we’re on a mission to create a climate positive world and a fossil free future through the power of chemistry. Learn more at

About LanzaTech

LanzaTech harnesses the power of biology and big data to create climate-safe materials and fuels. With expertise in synthetic biology, bioinformatics, Artificial Intelligence and Machine Learning coupled with engineering, LanzaTech has created a platform that converts waste carbon into new everyday products that would otherwise come from virgin fossil resources. LanzaTech’s first commercial scale gas fermentation plant has produced over 30M gallons of ethanol which is the equivalent of keeping over 150,000 metric tons of CO2 from the atmosphere. Additional plants are under construction globally. LanzaTech is based in Illinois, USA and employs more than 300 people. Further information is available at

About TotalEnergies

TotalEnergies is a global multi-energy company that produces and markets energies: oil and biofuels, natural gas and green gases, renewables and electricity. Our 105,000 employees are committed to energy that is ever more affordable, cleaner, more reliable and accessible to as many people as possible. Active in more than 130 countries, TotalEnergies puts sustainable development in all its dimensions at the heart of its projects and operations to contribute to the well-being of people.


Liz Crumpacker |


Liz Crumpacker |