ROI in Pharmaceutical R&D: How to Halt the Decline - ResearchAndMarkets.com

DUBLIN--(BUSINESS WIRE)--The "ROI in Pharmaceutical R&D: How to Halt the Decline" report has been added to ResearchAndMarkets.com's offering.

This report investigates recent years of performance of pharmaceutical and biopharmaceutical companies with respect to return on investment (ROI) in research and development (R&D), and to discuss ways that companies are trying to improve ROI through 2024.

Many factors enter into the calculation of ROI; this is not a straightforward calculation, especially if one does not have access to the company's internal accounting books. However, the fact that many factors enter into the calculation, also may be taken to mean that a number of factors might be adjusted or developed to improve ROI. Laying off employees is one way, but this is not effective longer-term unless the company is at the same time reorganizing for greater efficiency. Sanofi, for example, hit hard by pricing pressure in diabetes, started laying off 400 US sales employees in June 2019 but states that it is also undergoing a reorganization to its salesforce.

The most significant route to decreasing costs and improving failure rates is to cut off the development of a failing drug as early as possible in order to focus on potential winners. Pretty obvious - but how best to do this?

Many pharma and biotech companies are exploring the use of technology to make the most of clinical development and clinical trials. In the next three to five years:

• Robotic automation will streamline resources across the clinical trial value chain.
• Use of AI, ML and IT with Big Data will enable researchers to see larger trends and patterns in data, and to act on those trends earlier in the process.
• Clinical trials will become open, and trials will be better understood by the public.
• Clinical trials will become patient-centric and better integrated into medical systems, thereby becoming an integral part of health care.

The scope of this study begins with the challenges facing biotech and pharmaceutical companies today. It goes on to discuss regulatory approval processes in various countries, how these are changing, and the knock-on effects which the pharma/biotech companies will have to address. The report then reviews several key financial ratios, then discusses how to maximize clinical development success rate. We then go into how machine learning (ML) and artificial intelligence (AI), along with Big Data, are disrupting the pharma/biotech industry, in a positive way. The report then reviews the global markets for treatments for selected cancers, chronic diseases, cardiovascular disease, neurological diseases, infectious diseases and rare diseases. Chapter 15 discusses how companies need to deeply integrate ML, AI and Big Data into drug discovery and clinical testing - or risk falling behind the competition. The report wraps up with summaries of selected companies active in these spaces and beginning to utilize digital tools in R&D.

The Report Includes:

• 49 data tables and 30 additional tables
• An assessment of return on investment (ROI) in R&D by top pharmaceutical companies within the industry
• Analyses of the global market trends for various chronic disease areas, with data from 2016 to 2017, and projections of compound annual growth rates (CAGRs) through 2024
• Pipeline analysis of various therapeutic drugs with oncology being the largest, and coverage of ongoing clinical trials and promising forthcoming therapies in late stage etc.
• Outlining details of many factors involved in calculating ROI in R&D in pharma and how some of those factors are adjusted/developed to improve R&D ROI
• Discussion of the competitive landscape and key mergers and acquisition deals, partnerships, collaborations during the timeframe, 2014-2024
• Profile descriptions of top 15 pharmaceutical companies, their sales data, market capitalization and areas of R&D etc.

Companies Mentioned

• 23Andme
• Abbvie
• Allergan Plc
• Amgen Inc.
• Astellas Pharma Inc.
• Astrazeneca Plc
• Bayer Ag
• Biogen Idec
• Boehringer Ingelheim Gmbh
• Bristol-Myers Squibb Co.
• Celgene Corp.
• CSL Behring
• Eli Lilly And Co.
• Exscientia
• Gilead Sciences Inc.
• Glaxosmithkline Plc
• Johnson & Johnson Inc.
• Merck & Co., Inc.
• Novartis Ag
• Novo Nordisk A/S
• Numerate Inc.
• Pfizer Inc.
• Roche (F. Hoffman-La Roche Ag)
• Sanofi
• Vertex Pharmaceuticals

For more information about this report visit https://www.researchandmarkets.com/r/rk0shx

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