Global Cold Agglutinin Disease Market Spotlight 2019: Key Pipeline Drugs, Clinical Trials, Probability of Success, Licensing, Acquisition Deals, and Epidemiology - ResearchAndMarkets.com

DUBLIN--()--The "Market Spotlight: Cold Agglutinin Disease" report has been added to ResearchAndMarkets.com's offering.

This Market Spotlight report covers the Cold Agglutinin Disease market, comprising disease background and treatment information, key pipeline drugs, clinical trials, probability of success, licensing and acquisition deals, and an epidemiology overview.

Key Takeaways

  • There are only two industry-sponsored drugs in active clinical development for cold agglutinin disease, with one drug each in Phase II and Phase III.
  • Therapies in development for cold agglutinin disease target the complement pathway. These pipeline drugs are administered via the intravenous, subcutaneous, and intraocular/subretinal/subconjunctival routes.
  • The overall likelihood of approval of a Phase I autoimmune/immunology-other asset is 21.8%, and the average probability a drug advances from Phase III is 70.5%. Drugs, on average, take 10.1 years from Phase I to approval, compared to 9.0 years in the overall autoimmune/immunology space.
  • There have been only two licensing and asset acquisition deals involving cold agglutinin disease drugs during 2014-19. The largest deal was the $825m agreement in 2017 between Bioverativ and True North Therapeutics for the acquisition of TNT009 (now referred to as BIVV009 or sutimlimab).
  • The distribution of clinical trials across Phase I-III indicates that the majority of trials for cold agglutinin disease have been in the early and mid-phases of development, with 62.5% of trials in Phase I-II, and only 37.5% in Phase III.
  • The majority of clinical trial activity in the cold agglutinin disease space comprises completed trials.
  • Sanofi leads industry sponsors with the highest number of clinical trials for cold agglutinin disease.

Key Topics Covered:

OVERVIEW

KEY TAKEAWAYS

DISEASE BACKGROUND

Disease definition

Patient subtypes

Symptoms

Risk factors

Diagnosis

TREATMENT

Non-pharmacological treatment

Pharmacological treatment

EPIDEMIOLOGY

PIPELINE DRUGS

PROBABILITY OF SUCCESS

LICENSING AND ASSET ACQUISITION DEALS

PARENT PATENTS

CLINICAL TRIAL LANDSCAPE

Sponsors by status

Sponsors by phase

BIBLIOGRAPHY

APPENDIX

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Contacts

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Contacts

ResearchAndMarkets.com
Laura Wood, Senior Press Manager
press@researchandmarkets.com
For E.S.T Office Hours Call 1-917-300-0470
For U.S./CAN Toll Free Call 1-800-526-8630
For GMT Office Hours Call +353-1-416-8900