HIGH POINT, N.C.--(BUSINESS WIRE)--vTv Therapeutics Inc. (Nasdaq: VTVT), a clinical-stage biopharmaceutical company engaged in the discovery and development of orally administered treatments for Alzheimer’s disease and diabetes, today announced that it will make an oral presentation at the 2019 Alzheimer's Association International Conference (AAIC) held in Los Angeles, California, July 14 – 18, 2019.
The presentation will highlight data from the phase 3 STEADFAST Study and preceding phase 2b study of azeliragon to further support the biological hypothesis for the potential beneficial effects of azeliragon on the ADAS-cog and CDR-sb in patients with mild Alzheimer’s disease and type 2 diabetes.
Details of the presentation are below:
Presentation Title: Linking Diabetes and Alzheimer’s Disease through RAGE.
A Retrospective Analysis of Azeliragon Phase 2 and Phase 3 Studies
Session: O4-11 Clinical: Prevention (clinical) and Human Trials - Inflammation
Date and Time: Wednesday, July 17, 2019, 5:00 – 5:15 pm PT
Location: Concourse Hall 152
The presentation slides will be made available on the Publications page of the Company website.
Azeliragon, also known as TTP488, is an orally active small-molecule antagonist of the receptor for advanced glycation endproducts, RAGE. vTv Therapeutics discovered and developed azeliragon using its proprietary drug discovery platform, TTP Translational Technology®. A broad range of human pathologic and experimental biologic investigation suggests that RAGE ligand interactions lead to sustained inflammatory states that play a role in chronic diseases such as diabetes, inflammation, and Alzheimer’s disease. vTv is screening patients for a phase 2, randomized, double-blind, placebo-controlled 6-month proof of concept study evaluating azeliragon in patients with mild Alzheimer’s disease and type 2 diabetes.
About vTv Therapeutics
vTv Therapeutics Inc. is a public, clinical-stage biopharmaceutical company engaged in the discovery and development of orally administered small molecule drug candidates to fill significant unmet medical needs. vTv has a pipeline of clinical drug candidates led by programs for the treatment of diabetes, Alzheimer’s disease, and inflammatory disorders.
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