Zykadia (Ceritinib; Novartis) Drug Report 2017-2026 - ResearchAndMarkets.com

DUBLIN--()--The "Zykadia" report has been added to ResearchAndMarkets.com's offering.

Zykadia (ceritinib; Novartis) is a tyrosine kinase inhibitor that targets anaplastic lymphoma kinase (ALK). In most ALK-positive non-small cell lung cancer (NSCLC) cases, inversions in chromosome 2 cause ALK to fuse to echinoderm microtubule-associated protein-like 4.

This activates the ALK kinase domain and downstream signaling pathways responsible for excess cancer cell proliferation. ALK gene rearrangements are found more commonly in younger, non-smoking NSCLC patients and make up 3-5% of all NSCLC cases.

Key Topics Covered

  1. Drug Overview
  2. Product Profiles
  3. Zykadia : Non-small cell lung cancer (NSCLC)

LIST OF FIGURES

Figure 1: The authors drug assessment summary for Zykadia in non-small cell lung cancer

Figure 2: The authors drug assessment summary for ensartinib in non-small cell lung cancer

LIST OF TABLES

Table 1: Zykadia drug profile

Table 2: Zykadia pivotal trial data in non-small cell lung cancer

Table 3: Zykadia sales for NSCLC across the US, Japan, and five major EU markets, by country ($m), 2017-26

Table 4: Zykadia patient numbers for NSCLC across the US, Japan, and five major EU markets, by country, 2017-26

For more information about this report visit https://www.researchandmarkets.com/r/i2090h

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Related Topics: Lung Cancer Drugs

Contacts

ResearchAndMarkets.com
Laura Wood, Senior Press Manager
press@researchandmarkets.com
For E.S.T Office Hours Call 1-917-300-0470
For U.S./CAN Toll Free Call 1-800-526-8630
For GMT Office Hours Call +353-1-416-8900
Related Topics: Lung Cancer Drugs