Global Peripheral T-Cell Lymphoma (PTCL) Market Spotlight 2018-2026 - ResearchAndMarkets.com

DUBLIN--()--The "Market Spotlight: Peripheral T-Cell Lymphoma (PTCL)" report has been added to ResearchAndMarkets.com's offering.

This Market Spotlight report covers the Peripheral T-Cell Lymphoma market, comprising key marketed and pipeline drugs, clinical trials, upcoming events, probability of success, patent information, a 10-year disease incidence forecast, and licensing and acquisition deals, as well as presenting drug-specific revenue forecasts

Key Takeaways

  • The author estimates that in 2017, there were approximately 19,950 incident cases of peripheral T-cell lymphoma (PTCL) worldwide, and forecasts that number to increase to 23,880 incident cases by 2026.
  • It is estimated that the majority of diagnosed cases were in males in 2017.
  • The incidence of PTCL is highest among older individuals aged 60+ years. The approved drugs in the PTCL space focus on a wide variety of targets. These drugs are administered via the intravenous and oral routes.
  • The majority of industry-sponsored drugs in active clinical development for PTCL are in Phase II, with only one drug in Phase III. Therapies in the pipeline for PTCL focus on a wide variety of targets. The majority of pipeline drugs in development are administered intravenously, with a smaller number being tested in oral formulations.
  • High-impact upcoming events for drugs in the PTCL space comprise topline Phase II trial results for Darzalex and Zinapar. The overall likelihood of approval of a Phase I hematologic asset is 10.7%, and the average probability a drug advances from Phase III is 57.6%. Drugs, on average, take 8.7 years from Phase I to approval, compared to 9.2 years in the overall oncology space.
  • There have been 14 licensing and asset acquisition deals involving PTCL drugs during 2013-18. The $190m exclusive licensing agreement signed in October 2017 between Karyopharm and Ono Pharmaceutical for the development and marketing of Karyopharm's selinexor and KPT-8602 in South Korea, Hong Kong, Taiwan, Japan, and ASEAN countries was the largest deal during the period.
  • The clinical trials distribution across Phase I-IV indicates that the vast majority of trials for PTCL have been in the early and midphases of development, with 93% of trials in Phase I-II, and only 7% in Phase III-IV.
  • The US has a substantial lead in the number of PTCL clinical trials globally. The UK leads the major EU markets, while Japan has the top spot in Asia.
  • Clinical trial activity in the PTCL space is dominated by completed trials. Celgene has the highest number of completed clinical trials for PTCL, with nine trials.
  • Celgene leads industry sponsors with the highest number of clinical trials for PTCL, followed by Spectrum Pharmaceuticals.

Key Topics Covered:

OVERVIEW

KEY TAKEAWAYS

DISEASE BACKGROUND

Subtypes

TREATMENT

EPIDEMIOLOGY

MARKETED DRUGS

Approvals by country

PIPELINE DRUGS

RECENT EVENTS AND ANALYST OPINION

Adcetris for PTCL (October 1, 2018)

Cerdulatinib for PTCL (June 4, 2018)

KEY UPCOMING EVENTS

KEY REGULATORY EVENTS

Adcetris Speeds To PTCL Approval With Two-Week Review

PROBABILITY OF SUCCESS

LICENSING AND ASSET ACQUISITION DEALS

Onxeo Seeks Partner For Its Expanding Oncology Pipeline

PARENT PATENTS

REVENUE OPPORTUNITY

CLINICAL TRIAL LANDSCAPE

Sponsors by status

Sponsors by phase

Recent events

BIBLIOGRAPHY

Prescription information

APPENDIX

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Contacts

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Related Topics: Hematology

Contacts

ResearchAndMarkets.com
Laura Wood, Senior Press Manager
press@researchandmarkets.com
For E.S.T Office Hours Call 1-917-300-0470
For U.S./CAN Toll Free Call 1-800-526-8630
For GMT Office Hours Call +353-1-416-8900
Related Topics: Hematology