LONDON--(BUSINESS WIRE)--Technavio has announced their latest drug pipeline analysis report on malaria. The report includes a comprehensive research on the pipeline molecules under investigation by the pharmaceutical companies within the defined data collection period for the treatment of malaria. The report also includes a study of the pipeline molecules in various stages including, on-going clinical trials, discovery, and pre-clinical.
Malaria: An overview
Malaria is a life-threatening disease caused by the Plasmodium parasite, which is transmitted by infected female mosquitoes of the genus Anopheles. These infected mosquitoes release the Plasmodium parasite into the human’s bloodstream. These parasites move toward the liver where they mature and replicate. Later they spread through the bloodstream and infect healthy red blood cells (RBCs) in the body. They multiply inside the RBCs, causing fever, sweating, and nausea which occur in a cycle and last 2-3 days. Malaria can also be transmitted during organ transplantation, blood transfusion, and through shared needles and syringes.
Malaria mainly occurs in tropical countries, with the highest concentration in Africa. According to the World Bank, sub-Saharan Africa accounts for 90% of the global malaria cases. Countries in APAC such as India are also highly exposed to the disease. The World Bank has been supporting malaria control programs and financing the healthcare organizations in procuring preventive measures such as mosquito nets, antimalaria drugs, and diagnostic test kits.
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Malaria: Segmentation of pipeline molecules
Technavio’s research segments the pipeline molecules based on different phases of drug development including, therapies employed, route of administration (RoA), mechanism of action (MoA), therapeutic modality, and the targets for the drugs under development. In the current drug pipeline, the most preferred RoA remains through the oral mode, with more than 43% of the pipeline molecules administered through this mode.
Between companies and institutions, institutions led the drug development space for the treatment of malaria. Some of the key players include Agilvax, Eisai, Sanofi, Novartis, and GENVEC.
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Some of the key topics covered in the report include:
1. Scope of the Report
2. Regulatory Framework
3. Drug Development Landscape
- Drugs under development
4. Drug Development Strategies
- Therapies employed
- Route of administration
- Therapeutic modality
- Mechanism of action
5. Recruitment Strategies
- Geographical coverage
- Recruitment status
6. Key Companies
- Type of players
- Company overview
7. Discontinued and Dormant Molecules
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