NEW YORK--(BUSINESS WIRE)--Kadmon Holdings, Inc. (NYSE:KDMN) today announced that additional data from its ongoing Phase 2 clinical trial of KD025 in chronic graft-versus-host disease (cGVHD) will be highlighted in an oral presentation at the 23rd Congress of the European Hematology Association (EHA), to be held June 14-17, 2018 in Stockholm, Sweden.
Details for the presentation are as follows:
EHA Presentation Details
Date & Time: Saturday, June 16, 4:30 – 4:45 p.m. CEST
Title: KD025-208: A Phase 2 Open-Label Trial of KD025 for Steroid-Dependent Chronic Graft-Versus-Host Disease (cGVHD)
KD025 is a selective oral inhibitor of Rho-associated coiled-coil kinase 2 (ROCK2), a signaling pathway that mediates cell movement, shape, differentiation and function and is dysregulated in many chronic diseases, including cGVHD. In October 2017, KD025 received orphan drug designation from the U.S. Food and Drug Administration (FDA) for cGVHD. In April 2018, based on FDA guidance, Kadmon announced a planned open-label, pivotal study of KD025 in cGVHD.
cGVHD is a common and often fatal complication following hematopoietic stem cell transplantation, a procedure that is often used to treat patients with cancers such as myeloma or leukemia. With cGVHD, transplanted immune cells (graft) attack the patient’s cells (host), leading to inflammation and fibrosis in multiple tissues, including skin, mouth, eye, joints, liver, lung, esophagus and GI tract.
About Kadmon Holdings, Inc.
Kadmon Holdings, Inc. is a fully integrated biopharmaceutical company developing innovative products for significant unmet medical needs. Our product pipeline is focused on inflammatory and fibrotic diseases.
Forward Looking Statements
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