Lamictal & Lamictal XR (GlaxoSmithKline) Drug Overview 2018 - ResearchAndMarkets.com

DUBLIN--()--The "Drug Overview: Lamictal and Lamictal XR" report has been added to ResearchAndMarkets.com's offering.

Lamictal (GlaxoSmithKline) contains lamotrigine, a phenyltriazine antiepileptic drug that acts at voltage-sensitive sodium channels to stabilize neuronal membranes and inhibits the release of excitatory amino acid neurotransmitters.

Lamictal initially launched as an adjunctive treatment for epilepsy in the US and EU in 1995 and 1997, respectively. In June 2003, the US Food and Drug Administration approved Lamictal for the long-term maintenance treatment of adults with bipolar I disorder.

Lamictal boasts a strong clinical profile, possessing superior tolerability compared to atypical antipsychotics. As the only anticonvulsant indicated for the maintenance phase of bipolar disorder, Lamictal carved a niche for itself for patients with depressive episodes. While Lamictal is yet to be approved for bipolar depression, its significant efficacy makes it amenable to off-label use in patients experiencing acute bipolar depression.

This provides a prominent advantage to GlaxoSmithKline as it enjoys substantial market share in a less competitive space in the bipolar treatment algorithm without participating in the regulatory approval process. While Lamictal is clinically attractive, its commercial prospects in bipolar disorder are hampered by the widespread availability of lamotrigine generics.

Key Topics Covered

  1. Drug Overview
  2. Product Profiles
  3. Lamictal: Bipolar disorder
  4. Lamictal & Lamictal XR: Epilepsy

List of Figures

Figure 1: Lamictal for bipolar disorder - SWOT analysis

Figure 2: Drug assessment summary for Lamictal in bipolar disorder

Figure 3: Drug assessment summary for Lamictal in bipolar disorder

Figure 4: Lamictal/Lamictal XR for epilepsy - SWOT analysis

Figure 5: Drug assessment summary for Lamictal in epilepsy

Figure 6: Drug assessment summary for Lamictal in epilepsy

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Related Topics: Mental Disorders Drugs

Contacts

ResearchAndMarkets.com
Laura Wood, Senior Manager
press@researchandmarkets.com
For E.S.T. Office Hours Call 1-917-300-0470
For U.S./CAN Toll Free Call 1-800-526-8630
For GMT Office Hours Call +353-1-416-8900
Related Topics: Mental Disorders Drugs