Sickle Cell Anemia Market Spotlight 2018-2028: Key Pipeline and Marketed Drugs, Clinical Trials, Upcoming and Regulatory Events & Patent Information - ResearchAndMarkets.com

DUBLIN--()--The "Market Spotlight: Sickle Cell Anemia" report has been added to ResearchAndMarkets.com's offering.

This Market Spotlight report covers the sickle cell anemia market, comprising key pipeline and marketed drugs, clinical trials, upcoming and regulatory events, patent information, a 10-year disease prevalence forecast, and licensing and acquisition deals, as well as presenting drug-specific revenue forecasts.

Key Takeaways

  • The report estimates that in 2016, there were 3.2 million prevalent cases of sickle cell anemia worldwide, and forecasts that number to increase to 3.5 million prevalent cases by 2025.
  • Africa is estimated to have had 2.7 million prevalent cases of sickle cell anemia in 2016, accounting for 85% of worldwide cases. Endari, a patented drug treatment that involves an oral administration of L-glutamine, is the only US Food and Drug Administration approved drug for sickle cell anemia.
  • The majority of industry-sponsored drugs in active clinical development for sickle cell anemia are in Phase II. Therapies in mid- and late-stage development for sickle cell anemia focus on a wide variety of targets. The majority of the pipeline drugs in mid-to-late-stage development for sickle cell anemia are administered via the intravenous or oral routes, with one product being tested in both subcutaneous and intravenous formulation.
  • High-impact upcoming events in the sickle cell anemia space include topline Phase III trial results for voxelotor. There were eight licensing and asset acquisition activities involving sickle cell anemia drugs during 2013-18, three of which occurred in 2015. The $2,520m strategic research collaboration deal between Vertex Pharmaceuticals and CRISPR Therapeutics, for the discovery and development of drugs based on CRISPR-Cas9 technology, was the largest deal during the 2013-18 period.
  • The clinical trials distribution across Phase I-IV indicates that the majority of the drugs are in early and mid phases of development, with 80% of trials in Phase I-II, and only 20% in Phase III-IV.
  • The US has a substantial lead in the number of sickle cell anemia clinical trials globally, while the UK leads the major EU markets Clinical trial activity in the sickle cell anemia space is dominated by completed trials. Pfizer and Eli Lilly have the highest number of completed clinical trials for sickle cell anemia, with seven each.
  • Global Blood Therapeutics leads industry sponsors with the highest number of clinical trials for sickle cell anemia, followed by Novartis and Pfizer.

For more information about this report visit https://www.researchandmarkets.com/research/fs5lmk/sickle_cell?w=4

Contacts

ResearchAndMarkets.com
Laura Wood, Senior Manager
press@researchandmarkets.com
For E.S.T Office Hours Call 1-917-300-0470
For U.S./CAN Toll Free Call 1-800-526-8630
For GMT Office Hours Call +353-1-416-8900
Related Topics: Hematology

Contacts

ResearchAndMarkets.com
Laura Wood, Senior Manager
press@researchandmarkets.com
For E.S.T Office Hours Call 1-917-300-0470
For U.S./CAN Toll Free Call 1-800-526-8630
For GMT Office Hours Call +353-1-416-8900
Related Topics: Hematology