Tymlos (abaloparatide; Radius Health/Teijin) Drug Overview 2018 - ResearchAndMarkets.com

DUBLIN--()--The "Drug Overview: Tymlos" report has been added to ResearchAndMarkets.com's offering.

Tymlos (abaloparatide; Radius Health/Teijin) is a synthetic peptide analog of human parathyroid hormone-related protein (PTHrP), which binds to the same receptor as parathyroid hormone (PTH).

Endogenous PTHrP plays a central role in the regulation of endochondral bone development, with knockout mice not surviving past birth due to lack of proper bone development. Despite binding to the same receptor (PTHR1), PTHrP and PTH have different functions in vivo.

Although they both act to increase bone mineral density, PTHrP does not induce the subsequent unwanted bone resorption or hypercalcemic responses to the same extent as is seen with PTH. Compared with PTH, Tymlos has been shown to bind with a greater affinity to the conformation of PTHR that positively impacts bone formation.

Key Topics Covered:

Drug Overview

Product Profiles

Tymlos: Osteoporosis

List of Figures

Figure 1: Tymlos for osteoporosis - SWOT analysis

Figure 2: Drug assessment summary of Tymlos for osteoporosis

Figure 3: Drug assessment summary of Tymlos for osteoporosis

List of Tables

Table 1: Tymlos drug profile

Table 2: Tymlos Phase III trial data in osteoporosis

Table 3: Tymlos planned Phase III trials in osteoporosis

For more information about this report visit https://www.researchandmarkets.com/research/nf29p3/tymlos?w=4

Contacts

ResearchAndMarkets.com
Laura Wood, Senior Manager
press@researchandmarkets.com
For E.S.T Office Hours Call 1-917-300-0470
For U.S./CAN Toll Free Call 1-800-526-8630
For GMT Office Hours Call +353-1-416-8900
Related Topics: Musculoskeletal Disorders Drugs

Contacts

ResearchAndMarkets.com
Laura Wood, Senior Manager
press@researchandmarkets.com
For E.S.T Office Hours Call 1-917-300-0470
For U.S./CAN Toll Free Call 1-800-526-8630
For GMT Office Hours Call +353-1-416-8900
Related Topics: Musculoskeletal Disorders Drugs