CAMBRIDGE, Mass.--(BUSINESS WIRE)--KalVista Pharmaceuticals, Inc. (NASDAQ: KALV), a clinical stage pharmaceutical company focused on the discovery, development, and commercialization of small molecule protease inhibitors, today announced that data in support of KalVista’s ongoing development in diabetic macular edema (DME) has been accepted for oral presentation at The Association for Research in Vision and Ophthalmology (ARVO) 2018 Annual Meeting on May 1, 2018 in Honolulu, Hawaii.
“We look forward to presenting oral plasma kallikrein inhibitor data at ARVO 2018,” said Andrew Crockett, Chief Executive Officer of KalVista. “The potential to treat retinal edema orally would be a groundbreaking option for patients and we are pleased to share these findings with the medical and patient communities.”
The oral presentation details are as follows:
Novel Oral Plasma Kallikrein (PKal) Inhibitor KV123833 Blocks
VEGF-Mediated Retinal Vascular Hyperpermeability in a Murine Model of
Session: Neovascularization and Vascular Permeability, #365
Session Date/Start Time: May 1, 2018 at 3:45 PM in Room 314
About KalVista Pharmaceuticals, Inc.
KalVista Pharmaceuticals, Inc. is a pharmaceutical company focused on the discovery, development, and commercialization of small molecule protease inhibitors for diseases with significant unmet need. The initial focus is on inhibitors of plasma kallikrein, which is an important component of the body’s inflammatory response and which, in excess, can lead to increased vascular permeability, edema and inflammation. KalVista has developed a proprietary portfolio of novel, small molecule plasma kallikrein inhibitors initially targeting hereditary angioedema (HAE) and diabetic macular edema (DME). The Company has created a structurally diverse portfolio of oral plasma kallikrein inhibitors, and is advancing multiple drug candidates into Phase 1 clinical trials for HAE. KalVista’s most advanced program, an intravitreally administered plasma kallikrein inhibitor known as KVD001, has successfully completed its first-in-human study in patients with DME and began a Phase 2 clinical trial in 2017.
For more information, please visit www.kalvista.com.
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