SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Five Prime Therapeutics, Inc. (Nasdaq:FPRX), a clinical-stage biotechnology company focused on discovering and developing innovative immuno-oncology protein therapeutics, today announced that Charles D. Kaplan, Director of Immuno-Oncology Research at Five Prime, has been invited to give an oral presentation at the 2018 American Association for Cancer Research (AACR) Annual Meeting, being held April 14 - 18, 2018, in Chicago.
Presentation Title: FPA150: A recombinant, afucosylated,
fully human IgG1 monoclonal antibody for the treatment of malignancies
that express high levels of B7-H4
Presenter Name: Charles D. Kaplan
Session Type: Drug Development Track - Special Session
Session Title: New Drugs on the Horizon 1
Session Start Time: April 15, 2018 1:00 PM
Location: Room S103 - McCormick Place South (Level 1)
FPA150 is a novel, fully human, afucosylated monoclonal antibody targeting B7-H4. B7-H4 expression is observed in multiple solid tumors, including breast, bladder and gynecologic cancers, and has been documented to correlate with poor prognosis. FPA150 is designed with a dual mechanism of action: blocking the T cell checkpoint activity of B7-H4 as well as delivering potent antibody-dependent cell-mediated cytotoxicity against tumor cells expressing B7-H4. Five Prime anticipates initiating Phase 1 development of FPA150 during the first half of 2018.
About Five Prime
Five Prime Therapeutics, Inc. discovers and develops innovative therapeutics to improve the lives of patients with serious diseases. Five Prime's comprehensive discovery platform, which encompasses virtually every medically relevant extracellular protein, positions it to explore pathways in cancer, inflammation and their intersection in immuno-oncology, an area with significant therapeutic potential and the focus of the company's R&D activities. Five Prime has entered into strategic collaborations with leading global pharmaceutical companies and has promising product candidates in clinical and late preclinical development. For more information, please visit www.fiveprime.com or follow us on LinkedIn, Twitter and Facebook.
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