2018 Corlanor (ivabradine; Servier/Amgen/Ono Pharmaceutical) Drug Analysis - ResearchAndMarkets.com

DUBLIN--()--The "Drug analysis: Corlanor" drug pipelines has been added to ResearchAndMarkets.com's offering.

Corlanor (ivabradine; Servier/Amgen/Ono Pharmaceutical) blocks f-channels and inhibits the f-current, a modulator of the heart's pacemaker activity. Heart rate (HR) depends on the speed of diastolic depolarization of myocytes from the sinus node. By binding to the f-channels of sinoatrial cells, Corlanor blocks the inward flow of sodium and potassium.

This prolongs the myocytes' depolarization phase, and slows HR. A lower HR decreases cardiac oxygen consumption, and prolonged diastolic times increase myocardial perfusion. Corlanor's improvements in overall oxygen levels help to reduce cardiovascular risk. The drug's pure HR-lowering properties prevent it from affecting contractility, or intracardiac conduction.

Key Topics Covered:

Product Profiles

Corlanor: Chronic heart failure (CHF)

List of Figures

Figure 1: Corlanor for chronic heart failure - SWOT analysis

Figure 2: Drug assessment summary of Corlanor for chronic heart failure

Figure 3: Drug assessment summary of Corlanor for chronic heart failure

Figure 4: Corlanor sales for chronic heart failure across the US, Japan, and five major EU markets, by country, 2017-26

List of Tables

Table 1: Corlanor drug profile

Table 2: Corlanor pivotal phase III trial data in chronic heart failure

Table 3: Corlanor Phase II trial data in chronic heart failure

Table 4: Corlanor sales for chronic heart failure across the US, Japan, and five major EU markets, by country ($m), 2017-26

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Related Topics: Cardiovascular Drugs

Contacts

ResearchAndMarkets.com
Laura Wood, Senior Manager
press@researchandmarkets.com
For E.S.T Office Hours Call 1-917-300-0470
For U.S./CAN Toll Free Call 1-800-526-8630
For GMT Office Hours Call +353-1-416-8900
Related Topics: Cardiovascular Drugs