DUBLIN--(BUSINESS WIRE)--The "Cerebrotendinous Xanthomatosis Forecast in 18 Major Markets 2017-2027" report has been added to Research and Markets' offering.
Cerebrotendinous xanthomatosis (CTX) is a rare autosomal recessive lipid storage disease caused by mutations in the CYP27A1 gene encoding a cytochrome P450 oxidase, also known as sterol 27-hydroxylase. The lack of the functional enzyme results in a reduced production of chenodeoxycholic acid (CDCA) and cholic acid (CA), components of bile, as well as accumulation of cholestanol and cholesterol in different tissues, e.g., brain, tendons, lenses, bones and vessels. No genotype-phenotype correlations have been identified, and the phenotypic manifestation can vary even between identical twins.
This report provides the current prevalent population for CTX across 18 Major Markets (USA, Canada, France, Germany, Italy, Spain, UK, Japan, Russia, Brazil, Poland, Austria, The Netherlands, Turkey, India, China, Mexico, Argentina) split by gender and 5-year age cohort. Along with the current prevalence, the report also contains a disease overview of the risk factors, disease diagnosis and prognosis along with specific variations by geography and ethnicity.
Providing a value-added level of insight from the analysis team, several of the main symptoms and co-morbidities of CTX have been quantified and presented alongside the overall prevalence figures. These sub-populations within the main disease are also included at a country level across the 10-year forecast snapshot.
Key Topics Covered:
2. Cause of the Disease
3. Risk Factors & Prevention
4. Diagnosis of the Disease
5. Variation by Geography/Ethnicity
6. Disease Prognosis & Clinical Course
7. Key Comorbid Conditions / Features Associated With the Disease
8. Methodology for Quantification of Patient Numbers
9. Top-Line Prevalence for Cerebrotendinous Xanthomatosis
10. Comorbid Conditions of Cerebrotendinous Xanthomatosis Patients
11. Abbreviations Used in the Report
12. Other Publications
13. Patient-Based Databases
14. Patient-Based Offering
15. Online Pricing Data & Platforms
For more information about this report visit https://www.researchandmarkets.com/research/2lmn2k/cerebrotendinous