Market’s Only Cancer Immunotherapy ETF Launches

Exchange Traded Concepts Partners with Loncar Investments, ISE ETF Ventures, and Amplify Development on the Loncar Cancer Immunotherapy ETF (NASDAQ: CNCR)

  • Cancer immunotherapy companies are beneficially disrupting cancer treatment by deploying body’s own immune system to fight disease
  • ETF seeks to track index developed by biotechnology investor Brad Loncar
  • ETF offers diversified exposure to both pharmaceutical companies and clinical-stage biotechnology firms having immunotherapy focus

OKLAHOMA CITY--()--The first ETF to exclusively hold shares of public companies that are engaged in the research and development of therapies that treat cancer through the body’s immune system will begin trading on the NASDAQ this morning. The Loncar Cancer Immunotherapy ETF (CNCR) is based on the Loncar Cancer Immunotherapy Index, an innovative index developed by biotechnology investor Brad Loncar, and has an expense ratio of 0.79 percent.

Exchange Traded Concepts, LLC (ETC) partnered with Loncar Investments, ISE ETF Ventures, and Amplify Development LLC on the successful launch.

The fund includes both large pharmaceutical and growth-oriented biotechnology companies that are leading this disruptive approach to cancer treatment. Bristol-Myers Squibb (4.15% index weighting, ticker: BMY), Merck (3.89% index weighting, ticker: MRK), Juno Therapeutics (3.53% index weighting, ticker: JUNO) and Cellectis (2.98% index weighting, ticker: CLLS) are four of the index’s thirty holdings. Twenty-three of the holdings are growth companies, while the remaining seven are large-cap, value equities.

“Immunotherapy is changing the way many cancers are being treated,” said Brad Loncar, Chief Executive Officer of Loncar Investments. “This innovative field within biotechnology is expected to become the foundational treatment for cancer over the next ten years. We think it is important to give investors a benchmark to track the progress of this growing biotechnology sector, which over time will likely continue to have a positive impact on society.”

“The science of cancer immunotherapy is one of the most exciting areas within biotechnology,” said J. Garrett Stevens, CEO of Exchange Traded Concepts. “The Loncar Cancer Immunotherapy ETF allows investors to participate in the breakthrough in this well-defined sector in a diversified way. We are proud to deliver this product to the market.”

“We are excited to partner with Exchange Traded Concepts, Loncar Investments and Amplify Development to bring this new fund to market,” said Kris Monaco, Head of ISE ETF Ventures. “Our product portfolio focuses on funds that provide investors with exposure to targeted segments in first to market ETFs, and the Loncar Cancer Immunotherapy ETF is an outstanding fit with those objectives.”

“As the ETF market becomes more crowded, it can be challenging to find new investment themes that tap into a unique and compelling industry trend,” said Christian Magoon, CEO of Amplify Development LLC. “With his expertise in the biotechnology space, Brad Loncar has been able to do exactly that through the Loncar Cancer Immunotherapy Index, and I am pleased to partner with Brad, ETC and ISE ETF Ventures to offer this exciting new fund.”

Why immunotherapy: Cancer immunotherapy is an important sector in biotechnology that is changing the way many cancers are treated. While traditional medicines like chemotherapies often give cancer a broad punch, the benefit of using immunotherapy is derived from the immune system's dynamic nature and the way it can more precisely be tailored to fight the disease. Some immunotherapies have exhibited uncommon results in clinical trials including partial and complete responses in late stage cancer patients.

About Exchange Traded Concepts: ETC is carving out a niche as a portal to launch new, custom exchange-traded funds efficiently and cost-effectively through a complete turnkey solution. ETC is a private-label ETF advisor with passive and active exemptive relief from the Securities and Exchange Commission (SEC) to launch both domestic and international equity exchange traded funds under the Investment Company Act of 1940. For more information, please go to

About Loncar Investments: Loncar Investments, LLC, the provider of the Loncar Immunotherapy Index index, is committed to making the biotechnology space more approachable to a wider range of investors. The company is principally owned by biotech investor Brad Loncar. Mr. Loncar manages a biotech-focused family portfolio from his Lenexa, Kansas office. He can be followed on Twitter at @bradloncar and his commentary is available at

About ISE ETF Ventures: ISE ETF Ventures partners with issuers to launch exchange traded products (ETPs) such as exchange traded funds (ETFs), exchange traded notes (ETNs) and other similar product types. They also provide capital for the start-up and ongoing backstopping of new ETPs. Partners are able to leverage ISE ETF Ventures’ global experience and broad network of industry participants in order to grow their ETP presence and increase product issuance. Total assets under management for ETPs tied to ISE ETF Ventures indexes is approximately $3 billion.

ISE ETF Ventures is operated by ISE Holdings, which is a member of Eurex Group, and together they operate one of the largest transatlantic derivatives marketplaces. Eurex Group is owned by Deutsche Börse AG (Xetra: DB1).

About Amplify Development LLC: Amplify Development LLC is led by ETF industry veteran Christian Magoon and partners in the development and support of compelling third party ETFs. The firm is an affiliate of Amplify Investments LLC, an ETF Sponsor.

Opinions expressed are those of ETC, Loncar Investments and their partners and are subject to change, not guaranteed, and should not be considered investment advice.

Investing involves risk; Principal loss is possible. The Fund will invest in immunotherapy companies which are highly dependent on the development, procurement and marketing of drugs and the protection and exploitation of intellectual property rights. A company's valuation can also be greatly affected if one of its products is proven or alleged to be unsafe, ineffective or unprofitable. The costs associated with developing new drugs can be significant, and the results are unpredictable. The process for obtaining regulatory approval by the U.S. Food and Drug Administration or other governmental regulatory authorities is long and costly and there can be no assurance that the necessary approvals with be obtained and maintained. The Fund may invest in foreign securities, which involve political, economic, currency risk, greater volatility, and differences in accounting methods. The Fund is non-diversified meaning it may concentrate its assets in fewer individual holdings than a diversified fund. Therefore, the Fund is more exposed to individual stock volatility than a diversified fund. The Fund invests in smaller companies which may have more limited liquidity and greater volatility compared to larger companies. The Fund is not actively managed and may be affected by a general decline in market segments related to the index. The fund invests in securities included in, or representative of securities included in, the index, regardless of their investment merits . The performance of the fund may diverge from that of the Index and may experience tracking error to a greater extent than a fund that seeks to replicate an index.

The Fund's investment objectives, risks, charges and expenses must be considered carefully before investing. The summary and statutory prospectuses contain this and other important information about the investment company, and may be obtained by calling 800.617.0004 or visiting Read it carefully before investing.

Fund holdings are subject to change and should not be considered a recommendation to buy or sell any security. The % of assets held in the index and disclosed in this material is as of 10/7/2015. The ETF, once launched, seeks to replicate the % of holdings in the underlying index.

The NASDAQ Composite Index is a market capitalization-weighted index that is designed to represent the performance of the National Market System which includes over 5,000 stocks traded only over-the-counter and not on an exchange. One cannot invest directly in an index.

Diversification does not assure a profit nor protect against loss in a declining market.

The SEC does not approve or disapprove of any investment. (

The Loncar Cancer Immunotherapy ETF is distributed by Quasar Distributors, LLC.


Media Contact:
Joe Anthony for ISE ETF Ventures

Release Summary

Market’s Only Cancer Immunotherapy ETF Launches; Exchange Traded Concepts Partners with Loncar Investments, ISE ETF Venture, and Amplify Development on the Loncar Cancer Immunotherapy ETF (CNCR)


Media Contact:
Joe Anthony for ISE ETF Ventures