VANCOUVER, British Columbia--(BUSINESS WIRE)--The International Working Group on Antibody Validation, a group of leading authorities in the field of protein-binding technology, will hold its first meeting this week in Vancouver, Canada, coinciding with the Human Proteome Organization’s annual congress. The independent group, with operating expenses supported in part by Thermo Fisher Scientific, will develop guidelines for the validation of antibody specificity, functionality and reproducibility. Noted protein biochemist Mathias Uhlén, Ph.D., will chair the group.
“There is a critical need that has recently been highlighted in several high-profile publications for broadly accepted antibody quality and validation standards upon which the scientific community can rely,” said Dr. Uhlén, professor of microbiology, Royal Institute of Technology, Stockholm, Sweden. “I look forward to working with my esteemed fellow working group members to address this gap in a creative, timely and practical way and ensure the reliability of these essential tools of biomedical research.”
The goal of the working group is to develop common validation standards for antibodies. The working group will engage the broader scientific community in dialogue on the topic and interact with parallel initiatives in the field. Its goal is to publish consensus guidelines for both antibody users and providers. Delivery of the guidelines is targeted for fall 2016.
“Thermo Fisher Scientific is pleased to support the International Working Group on Antibody Validation. Antibody validation standards should provide users with confidence that an antibody can specifically recognize the intended target in appropriate assays,” said Klaus Lindpaintner, M.D., M.P.H., chief scientific officer, analytical technologies, Thermo Fisher Scientific. “Implementing optimized antibody validation standards should result in greater confidence among antibody users and more reliable and reproducible research outcomes.”
In addition to Dr. Uhlén, members of the International Working Group on Antibody Validation include:
- A. Bandrowski, Ph.D., Project Lead, Neuroscience Information Framework Project, University of California San Diego, San Diego, California
- Andrew Bradbury, Ph.D., Group Leader and Scientist, Biosciences Division, Los Alamos National Laboratory, Los Alamos, New Mexico
- Steven A. Carr, Ph.D., Director of Proteomics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts
- Emma Lundberg, Ph.D., Associate Professor, Department of Proteomics and Nanobiotechnology, Royal Institute of Technology, Stockholm, Sweden
- David L. Rimm, M.D., Ph.D., Professor of Pathology and of Medicine (Medical Oncology); Director of Pathology Tissue Services; Director of Translational Pathology, Yale University School of Medicine; New Haven, Connecticut
- Henry Rodriguez, Ph.D., M.B.A., Director, Office of Cancer Clinical Proteomics Research, National Cancer Institute, National Institutes of Health, Washington, D.C.
- Michael Snyder, Ph.D., Professor and Chair of Genetics; Director, Center for Genomics and Personalized Medicine; Stanford University, Stanford, California
- Tadashi Yamamoto, M.D., Ph.D., Research leader, Research Professor, Biofluid Biomarker Center (BB-C): Center of Innovation satellite (COI-s) Institute for Research Collaboration and Promotion, Niigata University; Niigata, Japan
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