DUBLIN--(BUSINESS WIRE)--Research and Markets (http://www.researchandmarkets.com/research/fl8dnt/hedgehog) has announced the addition of the "Hedgehog Signaling Pathway in Oncology Drug Pipeline Update 2015" report to their offering.
Aberrant activation of the Hedgehog pathway has been associated with a number of human malignancies including carcinoma of lung, esophagus, pancreas and prostate.
There are today 123 companies plus partners developing 150 Hedgehog pathway targeting drugs in 748 developmental projects in cancer. In addition, there are 3 suspended drugs and the accumulated number of ceased drugs over the last years amount to another 86 drugs.
Hedgehog Signaling Pathway In Oncology Drug Pipeline Update lists all drugs and gives you a progress analysis on each one of them. Identified drugs are linked to 118 different targets. All included targets have been cross-referenced for the presence of mutations associated with human cancer. To date 114 out of the 116 studied drug targets so far have been recorded with somatic mutations.
The software application lets you narrow in on these mutations and links out to the mutational analysis for each of the drug targets for detailed information. All drugs targets are further categorized on in the software application by 33 classifications of molecular function and with pathway referrals to BioCarta, KEGG, NCI-Nature and NetPath.
Pipeline Breakdown According to Number of Drugs
- Marketed - 7
- Pre-registration - 2
- Phase III - 12
- Phase II - 70
- Phase I - 84
- Preclinical - 87
- No Data - 3
- Suspended - 3
- Ceased - 86
For more information visit http://www.researchandmarkets.com/research/fl8dnt/hedgehog