GNI Forms Alliance with BIOBASE

- Further Enhances the Functions of Cell Illustrator 3.0 -

GNI and BIOBASE will further develop and market Cell Illustrator 3.0, a biological illustration and biopathway modeling software tool. (Graphic: Business Wire)

TOKYO--()--GNI Ltd, a leading biopharmaceutical company in Asia, today announced that it has formed a technology and business alliance with BIOBASE GmbH, a leading content provider of biological databases, knowledge tools and software for the life science industry. GNI and BIOBASE will further develop and market Cell Illustrator 3.0, a biological illustration and biopathway modeling software tool.

Cell Illustrator, which was developed by GNI along with the University of Tokyo, enables biologists to more easily create computer images and simulations of complex metabolic and gene regulatory pathways, signal transduction cascades and dynamic interactions. Originally developed to support GNIs own research efforts, it is recognized as an essential analytical tool in the research of gene networks.

Under the terms of the alliance, BIOBASE will develop an interface to connect Cell Illustrator to its biological database, which should provide users of the Cell Illustrator with easier access to pathway information and the ability to use the simulation function.

The functionality of the Cell Illustrator, combined with the new interface to the BIOBASE database, can enable pharmaceutical companies to analyze the mechanism of identified target genes and to utilize the biological database more efficiently. Users will also be able to input their own research data, analyze gene networks with their own personal computers and carry out model analysis based on pathways. Researchers will also be able to share their research content as well as being able to conduct final experiments based on the results of test simulations. Experimental resources and bio-based biological databases can also be used more efficiently.

GNI plans to provide its simulation tool Cell Illustrator Draw free of charge to BIOBASEs customers, which will enable them to visualize their database contents. BIOBASE customers include major global pharmaceutical companies, agricultural-biotechnology firms, government and municipal offices, universities, and public research institutes. BIOBASE has a range of databases that include gene regulation databases (TRANSFAC), signal transduction databases (TRANSPATH) and Proteomics Databases (PROTEOME). A modified version for TRANSPATH and TRANSFAC may soon be available and additional versions may be developed further. Optional functions such as advanced simulation and gene networks information are available at an additional charge.

GNIs Chairman, Chief Executive Officer and founder, Dr. Christopher Savoie, said, With the increasing importance of high speed data analysis in biological research and the significance of systems biology, GNI looks forward to helping companies and educational institutes around the world conduct research into gene networks and pathway models.

Professor Edger Wingender at BIOBASE added, We are excited to work with GNI to establish pathway models and to visualize our database. We believe Cell Illustrator will play an invaluable role in helping our customers conduct their research.

Notes to editors

About GNI

Founded in 2001, GNI, a leader in the field of integrated systems pharmacology, is an international biopharmaceutical company with operations in Japan, China, the U.K. and the U.S. GNI has used ethically approved methods to successfully map gene regulatory networks via a complex process of reverse-engineering. Furthermore, GNI has successfully developed the technology required to apply this data to drug development and discovery. In June 2005, Shanghai Genomics, which operates an integrated drug discovery platform combining genetic discovery and drug development, became an affiliate of GNI. In April 2006, GNI announced an investment in Beijing Continent Pharmaceutical which gives the company access to manufacturing and distribution in China. For further information, please visit


BIOBASE GmbH is a biological database company, which was established in 1997. It spun off from German Research Centre for Biotechnology, Branuschweig. The company provides databases for transcriptional factor, function of protein, and manually curated signal transduction cascades database. As all the database is curated by professionals, it enable users to extract only required information from extensive amount of data. Further details are available at:

About The Human Genome Center, Institute of Medical Science, University of Tokyo

The Human Genome Center was established by the University of Tokyos Institute of Medical Science in 1991 to oversee human genome planning for the Ministry of Education, Culture, Sport, Science and Technology. The Centers supercomputers analyze massive volumes of data for advanced research on cancer and other treatment-resistant illnesses. Professor Satoru Miyano and Assistant Professor Masao Nagasaki head the Centers research on DNA information analysis. Further details are available at:


Gavin Anderson & Company
Deborah Hayden or Anya Bailey, +81-5404-0640


Gavin Anderson & Company
Deborah Hayden or Anya Bailey, +81-5404-0640