Research and Markets: Essential Pharmaceutical and Environmental Analysis of Nano Chromatography and Capillary Electrophoresis

DUBLIN--(BUSINESS WIRE)--Research and Markets (http://www.researchandmarkets.com/research/b40546/nano_chromatograph) has announced the addition of John Wiley and Sons Ltd's new report "Nano Chromatography and Capillary Electrophoresis: Pharmaceutical and Environmental Analyses" to their offering.

Detection of drugs at low concentration is required in a variety of biological and medical situations, in order to avoid harmful side effects posed by some drug residues. The book details the instrumentation, detection, and application of nano chromatography (that is, any chromatographic and capillary electrophoretic method dealing with the detection of a sample at nano gram per liter or lower) and capillary electrophoresis in the analyses of biological and environmental samples. Methods discussed include: Nano Gas Chromatography, Nano Capillary Electrophoresis, Nano Chiral Chromatography, Micellar Electrokinetic Chromatography, Supercritical Fluid Chromatography, and Nano High Performance Liquid Chromatography.

Key Topics Covered:

Chapter 1: Introduction.

1. Nano Analyses.

2. Definition of Nano-Chromatography and Nano-Capillary Electrophoresis.

3. Nano-Chromatography and Nano-Capillary Electrophoresis.

4. Fabrication of Micro Devices.

5. Development in Nano Analyses.

6. Data Integration.

7. Protocol of Nano Analyses.

8. Scope of the Book.

9. Conclusion.

10. References.

Chapter 2: Fabrication of Micro Chips.

1. Introduction.

2. Substrates.

3. Techniques of Fabrication.

3.1 Glass Chips.

3.2 Quartz Chips.

3.3 Silica Chips.

3.4 Polymer Chips.

3.5 Plastic Chips.

3.6 Chips and PCR.

4. Surface Modification.

4.1 Modification by Polymers.

4.2 Modification by Silica Gel.

4.3 Modification by Monolithics.

4.4 Modification by Sulfonation.

5. Designs of Chips.

6. Bindings of Chips.

7. Conclusion.

8. References.

Chapter 3: Instrumentation of Nano-Chromatogrpahy and Nano-Capillary Electrophoresis.

1. Introduction.

2. Nano-Liquid Chromatography.

2.1 Mobile Phase Reservoirs.

2.2 Mobile Phases and Flow Calibration.

2.3 Mobile Phase Tubings.

2.4 Solvent Delivery Pump.

2.6 Sample Injector.

2.7 Separation Chips.

2.8 Detectors.

2.9 Recorder.

2.10 Sample Preparation Units.

3. Nano Capillary Electrophoresis.

3.1 Separation Chip.

3.2 Background Electrolyte and its Reservoirs.

3.3 Sample Injection Port.

3.4 Detectors.

3.5 Recorder.

3.6 Sample Preparation Units.

4. Conclusion.

5. References.

Chapter 4: Detection in Nano Chromatography and Nano Capillary Electrophoresis.

1. Introduction.

2. Mass Spectrometer Detectors.

3. Fluorescence Detectors.

4. Electrochemical Detectors.

5. Element Specific Detectors.

6. Miscellaneous Detectors.

7. Conclusion.

8. References.

Chapter 5: Sample Preparation in Nano Chromatography and Nano-Capillary Electrophoresis.

1. Introduction.

2. Sample Preparation.

3. Sampling.

3.1 Biological Samples.

3.1.1 Blood.

3.1.2 Urine.

3.1.3 Tissues.

3.1.4 Plants.

3.1.5 Food Stuffs.

3.2 Environmental Samples.

3.2.1 Air.

3.2.2 Water.

3.2.3 Sediment and Soils.

4. Preservation.

5. Filtration.

6. Digestion/Homogenization.

7. Extractions.

8. Clean-Up.

9. Pre-concentration.

10. Off-Line Nano-Sample Preparation Methods.

10.1 Nano Solid Phase Extractions.

10.2 Nano Membrane Extractions.

10.3 Nano Miscellaneous Extractions.

11. On-Line Nano-Sample Preparation Methods.

12. Conclusion.

13. References.

Chapter 6: Nano High Performance Liquid Chromatography.

1. Introduction.

2. Nano-HPLC.

3. Applications.

3.1 Nano-HPLC of Biological Matrices.

3.1.1 Proteomics.

3.1.2 Drugs Development and Design.

3.1.3 Environmental Analysis.

4. Optimization of Separations in Nano-HPLC.

5. Trouble Shooting in Nano-HPLC.

6. Conclusion.

7. References.

Chapter 7: Nano Capillary Electro-Chromatography and Nano Micellar Electrokinetic Chromatography.

1. Introduction.

2. Nano Capillary Electro-Chromatography.

2.1 Biological Samples.

2.2 Environmental Samples.

2.3 Mechanism of Separation.

3. Nano Micellar Electrokinetic Chromatography.

3.1 Biological Samples.

3.2 Environmental Samples.

3.3 Mechanisms of Separation.

4. Conclusion.

5. References.

Chapter 8: Nano Capillary Electrophoresis.

1. Introduction.

2. Optimization.

3. Applications.

3.1 Proteomics.

3.2 Genomics.

3.3 Amino Acids.

3.4 Drugs Development and Design.

3.5 Enzymes and Hormones.

3.6 Biological Fluids.

3.7 Foods and Beverages.

3.8 Viruses and Bacteria.

3.9 Explosives.

3.10 Environmental Analyses.

3.11 Miscellaneous Applications.

4. Mechanism of Separation.

5. Conclusion.

6. References.

Chapter 9: Chiral Separations by Nano Liquid Chromatography and Nano Capillary Electrophoresis.

1. Introduction.

2. Nano Liquid Chromatography.

3. Nano Capillary Electrophoresis.

4. Mechanisms of Chiral Separations.

5. Conclusion.

6. References.

Chapter 10: Perspectives of Nano Analyses.

1. Introduction.

2. Future of Micro Fluidic Devices.

3. Future Challenges.

4. Conclusion.

5. References.

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