The research study covers the present scenario and growth prospects of the global humanized mouse model market for 2017-2021. To calculate the market size, the report considers the revenue generated from the sales of various humanized mouse model products.
The global humanized mouse model market is growing. This is due to the growing number of applications of humanized mouse models in fields such as oncology, immunology, neuroscience, and toxicology. Humanized mouse models are being extensively used to study disease mechanisms, drug responses, and target identification to develop new drugs or therapies. Mice are also genetically engineered to assess immune responses, which are similar to humans.
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Technavio analysts highlight the following three factors that are contributing to the growth of the global humanized mouse model market:
- Increasing use of mice-based research
- Growing adoption of personalized medicine
- Innovative applications
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Increasing use of mice-based research
Rats and mice are ideal models for biotechnology and related medical research. This is because they offer certain genetic and physiological advantages when compared with other species, which makes them ideal replacements for humans. Rats, mice, and humans share approximately 95% of their genetic makeup. Hence, their anatomical and physical functions can be studied in greater detail. This information can be applied to human research to develop advanced therapies.
Amber Chourasia, a lead lab equipment research analyst at Technavio, says, “Identifying hearing defects is a major advantage of using rats. The origins of some gene defects that are responsible for hearing loss are similar in both species. Genetically identical inbred strains of mice, which contain a single mutated gene, are valuable in recognizing gene function.”
Growing adoption of personalized medicine
Personalized medicine, also called precision medicine or individualized medicine, is an emerging field of medicine. It identifies specific biomarkers to assess the best treatment for each patient. Mice have been used to develop personalized medicine for cancer. Researchers have developed the PDX cancer model.
“The growing demand for personalized medicine will increase the adoption of humanized mouse models. For instance, Jackson Laboratory has developed around 450 unique PDX oncology mice models for disorders such as acute myeloid leukemia and bladder, breast, lung, pancreatic, and ovarian cancers,” adds Amber.
Microorganisms are great models for studying cell cycles. However, for human studies, mice are preferred as they closely resemble humans in the genetic makeup. Mice offer natural induction with diseases such as diabetes, cancer, glaucoma, and osteoporosis (OPO), which affect their entire immune system.
In the recent years, researchers have explored several innovative genetic technologies to produce customized models for a wide range of diseases and to study the function of targeted genes. However, the creation transgenic mice is a significant advancement. In transgenic mice, a new gene is implanted into the animal's germline.
- Horizon Discovery
- Taconic Biosciences
- Jackson Laboratory
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