Rheumatoid Arthritis Heat Map and Analysis 2015-2022 - Research and Markets

DUBLIN--()--Research and Markets has announced the addition of the "Rheumatoid Arthritis - Heat Map and Analysis" report to their offering.

Rheumatoid Arthritis (RA) is a chronic, progressive and currently incurable autoimmune disease that primarily affects the joints. Disease progression results in stiffness and pain, especially in the hands and feet, which hinders the mobility of the patient and can have a substantial impact on quality of life.

Therapeutic options for the treatment of RA have grown rapidly over the past two decades, having also expanded to encompass a number of highly successful biologics. Although clinically and commercially successful, there are a number of unmet needs in this market.

The differences between many of these products are relatively nuanced, and must be understood fully by companies seeking to position a novel drug in this market. This tabular heat map framework, designed to provide an easily digestible summary of these clinical characteristics, provides detailed readouts of all late-stage clinical trial results for products in the RA market and Phase III pipeline. These are split along lines of therapy, and so are reflective of the treatment algorithm used in the clinic.

All safety and efficacy endpoints reported in these trials are displayed, for both the drug and placebo groups. In addition, key study characteristics such as the size, composition and patient segment of the study population, are provided. These results are presented in a visually accessible, color-coded manner in order to maximize ease-of-use.

The accompanying text provides a detailed analysis of the clinical benchmarks set by the current market landscape, and the anticipated changes to these benchmarks, and to the treatment algorithm, as a result of the late-stage pipeline.

Scope

- The rheumatoid arthritis market landscape is expected to change substantially with the advent of promising novel pipeline products.

- What are the clinical characteristics of currently approved therapies for rheumatoid arthritis, in terms of specific safety and efficacy parameters?

- What are the key unmet needs in this indication, and which clinical safety and efficacy parameters are the most closely linked to them?

- How will current late-stage IL-6 inhibitors affect the market for biologic DMARDs, and are they able to yield comparable clinical efficacy results to TNF-a therapies?

- With four targeted synthetic DMARDs present in the late-stage pipeline, do they have sufficient differentiating characteristics to make a strong impact on the market?

- How will the influx of biosimilar TNF-a inhibitors affect the competitive landscape?

Key Topics Covered:

1. Table of Contents

2. Introduction

3. Marketed Products

3.1 Overview

3.2 Conventional Synthetic Disease Modifying Anti-Rheumatic Drugs

3.3 Anti-Tumor Necrosis Factor Alpha Biologic Disease Modifying Anti-Rheumatic Drugs, with or without Concomitant Conventional Synthetic Disease Modifying Anti-Rheumatic Drugs

3.4 Non Anti-Tumor Necrosis Factor Alpha (TNFa) Biologic Disease Modifying Anti-Rheumatic Drugs, with or without Concomitant Conventional Synthetic Disease Modifying Anti-Rheumatic Drugs

3.5 Targeted Synthetic Disease Modifying Anti-Rheumatic Drugs with or without Concomitant Conventional Synthetic Disease Modifying Anti-Rheumatic Drugs

4. Pipeline Products

4.1 Changes to Conventional Synthetic Disease Modifying Anti-Rheumatic Drugs, 2015-2022

4.2 Changes to Anti-Tumor Necrosis Factor Alpha Biologic Disease Modifying Anti-Rheumatic Drugs, with or without Concomitant Conventional Synthetic Disease Modifying Anti-Rheumatic Drugs, 2015-2022

4.3 Changes to Non-Anti-Tumor Necrosis Factor Alpha Biologic Disease Modifying Anti-Rheumatic Drugs, with or without Concomitant Conventional Synthetic Disease Modifying Anti-Rheumatic Drugs, 2015-2022

4.4 Changes to Targeted Synthetic Disease Modifying Anti-Rheumatic Drugs with or without Concomitant Conventional Synthetic Disease Modifying Anti-Rheumatic Drugs, 2015-2022

5. Appendix

For more information about this report visit http://www.researchandmarkets.com/research/4d6c2f/rheumatoid

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press@researchandmarkets.com
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Contacts

Research and Markets
Laura Wood, Senior Manager
press@researchandmarkets.com
For E.S.T Office Hours Call 1-917-300-0470
For U.S./CAN Toll Free Call 1-800-526-8630
For GMT Office Hours Call +353-1-416-8900
U.S. Fax: 646-607-1907
Fax (outside U.S.): +353-1-481-1716