The research study covers the present scenario and growth prospects of the global hemophilia drugs market for 2016-2020. To calculate the market size, the report considers revenue generated from the sales of drugs used for the treatment of hemophilia, including hemophilia A, hemophilia B, and inhibitors. The report also considers the revenues to be generated from the sales of drugs that are expected to be launched into the market along with the decline in revenues from the patent expiries of the marketed drugs during the forecast period.
According to Sapna Jha, a lead analyst at Technavio for infectious and rare diseases research, “With the growing rates of diagnosis, the discrepancy between emerging countries' usage of replacement factor per capita versus that of the US and Europe will shorten over next couple of years. Additionally, the increasing convenience of the treatment regimen with the introduction of prophylactic use and growing expenditure on healthcare will improve the per capita consumption of replacement factor in developing countries, which augurs well for the growth of the market.”
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Technavio healthcare and life sciences analysts highlight the following three factors that are contributing to the growth of the global hemophilia drugs market:
- Focus on prophylactic treatment
- Drugs with prolonged action
- Improved diagnostic procedures
Focus on prophylactic treatment
The prophylactic treatment approach prevents spontaneous bleeding episodes, increases the quality of life in terms of physical activities, and retains the level of clotting factors above a baseline. It also reduces joint damage and suffering from pain. Most short-acting therapeutics exhibit immunogenic reactions, which led to people adopting long-acting therapeutics. “Many of these long-acting therapeutics are under development and expected to be launched during the forecast period. Thus, the shift in treatment focus toward prophylaxis due to its advantages drives the market,” says Sapna.
Drugs with prolonged action
Earlier, parenteral formulations for treating hemophilia B required frequent administration of replacement factors. Drugs with favorable pharmacokinetic profiles, including prolonged mechanism of action are fast gaining acceptance among physicians and individuals. These long-acting formulations reduce the need for repeated medication, thus reducing injection site pain. ALPROLIX by Biogen is one such drug. It is a long-acting recombinant coagulation factor IX and was launched by the company in 2014. Prolix by Baxalta and BeneFIX by Pfizer are other long-acting formulations. Currently, many other long-acting drug candidates are at various developmental stages. For instance, N9-GP (NN7999) by Novo Nordisk is a long-acting formulation currently under Phase III developmental stage.
Improved diagnostic procedures
It is estimated that approximately two-thirds of hemophilia patients are from the emerging markets, especially in countries such as Brazil, Russia, China, India, Mexico, Argentina, and Turkey. However, less than 20% of these individuals are treated with hemophilia therapeutics due to the lack of availability of proper standard diagnostic methods.
However, increased healthcare spending in these countries is helping improve the diagnosis of hemophilia patients, thus,driving the adoption rate of hemophilia drugs. This upward momentum in the diagnosed patients and hemophilia drug adoption rate will further help improve the market penetration of hemophilia therapeutics in these countries. This presents a great opportunity for vendors to improve their markets in these countries, which, in turn, will drive the growth of the global hemophilia drugs market.
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