DUBLIN--(BUSINESS WIRE)--Research and Markets (http://www.researchandmarkets.com/research/zzmkrg/the_mapk) has announced the addition of the "The MAPK Signaling Pathway in Oncology Drug Pipeline Update 2015" report to their offering.
The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration.
There are today 250 companies plus partners developing 311 The MAPK signaling pathway targeting drugs in 1316 developmental projects in cancer. In addition, there are 2 suspended drugs and the accumulated number of ceased drugs over the last years amount to another 190 drugs.
The MAPK Signaling Pathway In Oncology Drug Pipeline Update lists all drugs and gives you a progress analysis on each one of them. Identified drugs are linked to 180 different targets. All included targets have been cross-referenced for the presence of mutations associated with human cancer. To date 177 out of the 179 studied drug targets so far have been recorded with somatic mutations.
The software application lets you narrow in on these mutations and links out to the mutational analysis for each of the drug targets for detailed information. All drugs targets are further categorized on in the software application by 40 classifications of molecular function and with pathway referrals to BioCarta, KEGG, NCI-Nature and NetPath.
Pipeline Breakdown According to Number of Drugs
- Marketed - 29
- Pre-registration - 4
- Phase III - 42
- Phase II - 130
- Phase I - 143
- Preclinical - 162
- No Data - 8
- Suspended - 2
- Ceased - 190
Delivery Format: Desktop App plus Online Access to Updates (One Year)
For more information visit http://www.researchandmarkets.com/research/zzmkrg/the_mapk